Ptges Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ptges
prostaglandin E synthase
MGI:1927593

15 phenotypes from 3 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ptges^tm1.1Gaf/Ptges^tm1.1Gaf Lyz2^tm1(cre)Ifo/Lyz2⁺ involves: 129 * C57BL/6	abnormal leukocyte physiology	J:210141
	abnormal vascular wound healing	J:210141
	decreased prostaglandin level	J:210141
	increased leukocyte cell number	J:210141
	increased prostaglandin level	J:210141
Ptges^tm1.1Gaf/Ptges^tm1.1Gaf Tg(Tagln-cre)1Her/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal vascular wound healing	J:210141
	normal cardiovascular system phenotype	J:210141
	decreased prostaglandin level	J:210141
	increased prostaglandin level	J:210141
Ptges^tm1.1Gaf/Ptges^tm1.1Gaf Tg(Tek-cre)1Ywa/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal vascular wound healing	J:210141
	normal cardiovascular system phenotype	J:210141
	decreased prostaglandin level	J:210141
	increased prostaglandin level	J:210141
Ptges^tm1Aki/Ptges^tm1Aki B6.129P2-Ptges^tm1Aki	edema	J:197334
Ptges^tm1Aki/Ptges^tm1Aki B6.129P2-Ptges^tm1Aki	increased susceptibility to type I hypersensitivity reaction	J:197334
Ptges^tm1Aki/Ptges^tm1Aki involves: 129P2/OlaHsd	decreased leukotriene level	J:92047
Ptges^tm1Aki/Ptges^tm1Aki involves: 129X1/SvJ * C57BL/6	abnormal inflammatory response	J:91821
	abnormal prostaglandin level	J:91821
	chronic inflammation	J:91821
	impaired macrophage chemotaxis	J:91821
Ptges^tm1Lpa/Ptges^tm1Lpa DBA/1LacJ-Ptges^tm1Lpa	abnormal pain threshold	J:89960
	decreased inflammatory response	J:89960, J:90980
	decreased prostaglandin level	J:106147

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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