Trps1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Trps1
transcriptional repressor GATA binding 1
MGI:1927616

77 phenotypes from 6 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(Tyr,Col1a1-Trps1)1Brle/0 involves: FVB/N	abnormal dental pulp cavity morphology	J:233272
	abnormal dentin mineralization	J:233272
	abnormal dentin morphology	J:233272
	abnormal incisor morphology	J:233272
	abnormal mastication	J:233272
	brittle teeth	J:233272
	postnatal growth retardation	J:233272
	premature death	J:233272
Trps1^{em1(IMPC)Wtsi}/Trps1⁺ C57BL/6N-Trps1^{em1(IMPC)Wtsi}/Wtsi	decreased fasting circulating glucose level	J:211773
Trps1^{em1(IMPC)Wtsi}/Trps1^{em1(IMPC)Wtsi} C57BL/6N-Trps1^{em1(IMPC)Wtsi}/Wtsi	preweaning lethality, complete penetrance	J:211773
Trps1^m1Anu/Trps1^m1Anu C57BL/6NCrlAnu-Trps1^m1Anu	normal immune system phenotype	J:104190
Trps1^tm1.1Shiv/Trps1⁺ either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)	arched palate	J:80615
	decreased bone mineral density	J:80615
	decreased hair follicle number	J:80615
	kyphoscoliosis	J:80615
Trps1^tm1.1Shiv/Trps1^tm1.1Shiv either: (involves: 129/SvEv * 129S4/SvJae) or (involves: 129S4/SvJae * C57BL/6J)	abnormal basicranium morphology	J:288954
	abnormal cranial cartilage development	J:288954
	abnormal endochondral bone ossification	J:288954
	abnormal mandibular angle morphology	J:288954
	abnormal nasal septum morphology	J:288954
	abnormal nose morphology	J:288954
	abnormal secondary palate development	J:288954
	absent presphenoid bone	J:288954
	cleft palate	J:288954
	delayed palatal shelf elevation	J:288954
	delayed tooth eruption	J:288954
	downturned snout	J:288954
	mandibular condyloid process hypoplasia	J:288954
	mandibular coronoid process hypoplasia	J:288954
	maxillary zygomatic process hypoplasia	J:288954
	neonatal lethality, complete penetrance	J:288954
	palatal shelves fail to meet at midline	J:288954
	short mandible	J:288954
	short snout	J:288954
	small basisphenoid bone	J:288954
	vomer bone hypoplasia	J:288954
	zygomatic arch hypoplasia	J:288954
Trps1^tm1.1Shiv/Trps1^tm1.1Shiv either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)	abnormal pulmonary alveolus epithelial cell morphology	J:80615
	abnormal pulmonary alveolus morphology	J:80615
	abnormal rib morphology	J:80615
	abnormal thoracic cage shape	J:80615
	absent vibrissae	J:80615
	atelectasis	J:80615
	decreased hair follicle number	J:80615
	delayed endochondral bone ossification	J:80615
	hunched posture	J:80615
	micrognathia	J:80615
	neonatal lethality, complete penetrance	J:80615
	respiratory failure	J:80615
	scoliosis	J:80615
	small thoracic cage	J:80615
	thick pulmonary interalveolar septum	J:80615
	thin ribs	J:80615
Trps1^tm1Shiv/Trps1^tm1Shiv either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)	neonatal lethality, complete penetrance	J:80615
Trps1^tm1Ymur/Trps1⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	sparse hair	J:130140
Trps1^tm1Ymur/Trps1^tm1Ymur involves: 129S1/Sv * 129X1/SvJ	abnormal epidermal layer morphology	J:220362
	abnormal hair follicle development	J:220362
	decreased hair follicle number	J:220362
Trps1^tm1Ymur/Trps1^tm1Ymur involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal bone ossification	J:130140
	abnormal branching involved in ureteric bud morphogenesis	J:157308
	abnormal chondrocyte morphology	J:130140
	abnormal hair follicle morphology	J:130140
	abnormal kidney development	J:157308
	abnormal kidney interstitium morphology	J:157308
	abnormal lung morphology	J:130140
	abnormal metanephric mesenchyme morphology	J:157308
	abnormal sternum ossification	J:130140
	abnormal thoracic cage morphology	J:130140
	abnormal trachea morphology	J:130140
	absent tracheal cartilage rings	J:130140
	cyanosis	J:130140
	decreased length of long bones	J:130140
	decreased nephron number	J:157308
	decreased renal glomerulus number	J:157308
	disproportionate dwarf	J:130140
	increased rib number	J:130140
	neonatal lethality, complete penetrance	J:130140
	respiratory distress	J:130140
	short mandible	J:130140
	short maxilla	J:130140
	short sternum	J:130140
	small lung	J:130140
	split sternum	J:130140
	thick pulmonary interalveolar septum	J:130140

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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