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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Inpp5e
inositol polyphosphate-5-phosphatase E
MGI:1927753
37 phenotypes from 4 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Inpp5em1Tc/Inpp5em1Tc
involves: C57BL/6J * FVB/N 		abnormal nervous system morphology J:186861
abnormal neural tube morphology J:186861
anophthalmia J:186861
exencephaly J:186861
microphthalmia J:186861
Inpp5etm1.1(KOMP)Vlcg/Inpp5e+
C57BL/6N-Inpp5etm1.1(KOMP)Vlcg/Ucd 		eye hemorrhage J:211773
Inpp5etm1.1(KOMP)Vlcg/Inpp5etm1.1(KOMP)Vlcg
C57BL/6N-Inpp5etm1.1(KOMP)Vlcg/MbpMmucd 		abnormal craniofacial morphology J:211773
abnormal embryo size J:211773
abnormal eye morphology J:211773
abnormal forebrain morphology J:211773
abnormal hindbrain morphology J:211773
abnormal limb morphology J:211773
abnormal midbrain morphology J:211773
abnormal neural tube closure J:211773
anophthalmia J:211773
edema J:211773
microphthalmia J:211773
polydactyly J:211773
Inpp5etm1.1(KOMP)Vlcg/Inpp5etm1.1(KOMP)Vlcg
C57BL/6N-Inpp5etm1.1(KOMP)Vlcg/Ucd 		preweaning lethality, complete penetrance J:211773
Inpp5etm1.1Ssch/Inpp5etm1.2Ssch
Tg(CAG-cre/Esr1*)5Amc/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA 		abnormal retina photoreceptor layer morphology J:152712
increased body weight J:152712
kidney cortex cyst J:152712
Inpp5etm1.2Ssch/Inpp5etm1.2Ssch
involves: 129S1/Sv * 129X1/SvJ 		abnormal cilium morphology J:152712
abnormal eye development J:152712
abnormal metacarpal bone morphology J:152712
abnormal phalanx morphology J:152712
abnormal renal glomerular capsule morphology J:152712
abnormal renal tubule epithelial cell primary cilium morphology J:152712
anencephaly J:152712
anophthalmia J:152712
cleft palate J:152712
delayed endochondral bone ossification J:152712
embryonic lethality during organogenesis, incomplete penetrance J:152712
exencephaly J:152712
kidney cortex cyst J:152712
lethality throughout fetal growth and development, incomplete penetrance J:152712
neonatal lethality, complete penetrance J:152712
palatal shelf hypoplasia J:152712
palatal shelves fail to meet at midline J:152712
polycystic kidney J:152712
postaxial polydactyly J:152712
split sternum J:152712
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory