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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pglyrp2
peptidoglycan recognition protein 2
MGI:1928099
18 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Pglyrp2tm1Lky/Pglyrp2tm1Lky
involves: 129S4/SvJae * C57BL/6 		abnormal macrophage physiology J:159600
abnormal tumor necrosis factor level J:159600
decreased circulating interleukin-6 level J:159600
decreased susceptibility to bacterial infection induced morbidity/mortality J:159600
Pglyrp2tm1Rdz/Pglyrp2tm1Rdz
C.129S-Pglyrp2tm1Rdz 		abnormal circulating chemokine level J:178054
decreased susceptibility to induced arthritis J:178054
Pglyrp2tm1Rdz/Pglyrp2tm1Rdz
involves: 129S/SvEv * BALB/c 		abnormal chemokine secretion J:178053
abnormal crypts of Lieberkuhn morphology J:178053
abnormal gut flora balance J:178053
abnormal intestinal epithelium morphology J:178053
abnormal intestinal goblet cell morphology J:178053
abnormal intestinal mucosa morphology J:178053
gastrointestinal hemorrhage J:178053
increased interleukin-6 secretion J:178053
increased susceptibility to induced colitis J:178053
increased susceptibility to xenobiotic induced morbidity/mortality J:178053
intestinal ulcer J:178053
weight loss J:178053
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory