Mrps22 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mrps22
mitochondrial ribosomal protein S22
MGI:1928137

29 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mrps22^{tm1.1(KOMP)Vlcg}/Mrps22⁺ B6N(Cg)-Mrps22^{tm1.1(KOMP)Vlcg}/J	decreased bone mineral content	J:211773
	decreased bone mineral density	J:211773
	decreased circulating creatinine level	J:211773
	decreased lean body mass	J:211773
	hyperactivity	J:211773
	increased leukocyte cell number	J:211773
	increased mean corpuscular hemoglobin concentration	J:211773
	increased total body fat amount	J:211773
Mrps22^{tm1.1(KOMP)Vlcg}/Mrps22^{tm1.1(KOMP)Vlcg} B6N(Cg)-Mrps22^{tm1.1(KOMP)Vlcg}/J	embryonic lethality prior to organogenesis	J:211773
	prenatal lethality, complete penetrance	J:261971
	preweaning lethality, complete penetrance	J:211773
Mrps22^{tm1.1(KOMP)Vlcg}/Mrps22^{tm1.1(KOMP)Vlcg} C57BL/6N-Mrps22^{tm1.1(KOMP)Vlcg}/JMmucd	abnormal cell cycle checkpoint function	J:290315
	abnormal embryonic epiblast morphology	J:290315
	abnormal mitochondrial ATP synthesis coupled electron transport	J:290315
	abnormal mitochondrial crista morphology	J:290315
	abnormal mitochondrial morphology	J:290315
	abnormal mitochondrial physiology	J:290315
	abnormal respiratory electron transport chain	J:290315
	absent allantois	J:290315
	absent head fold	J:290315
	absent primitive node	J:290315
	normal cellular phenotype	J:290315
	decreased cellular ATP level	J:290315
	decreased embryo size	J:290315
	embryonic growth arrest	J:279207, J:290315
	embryonic growth retardation	J:279207, J:290315
	embryonic lethality between implantation and placentation, complete penetrance	J:279207, J:290315
	failure of primitive streak formation	J:279207, J:290315
	failure to gastrulate	J:279207, J:290315

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