Elf4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Elf4
E74 like ETS transcription factor 4
MGI:1928377

22 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Elf4^em1Hdu/Elf4^em1Hdu C57BL/6-Elf4^em1Hdu	abnormal CD4-positive T cell differentiation	J:328935
	abnormal interferon level	J:328935
	abnormal interleukin level	J:328935
	abnormal macrophage physiology	J:328935
	abnormal tumor necrosis factor level	J:328935
	increased susceptibility to viral infection	J:328935
Elf4^tm1Nim/Elf4^tm1Nim B6.129S1-Elf4^tm1Nim	abnormal definitive hematopoiesis	J:107070
	abnormal hematopoietic stem cell morphology	J:107070
	abnormal inflammatory response	J:79568
	abnormal lymphocyte morphology	J:79568
	abnormal lymphocyte physiology	J:79568
	abnormal NK cell physiology	J:79568
	abnormal T cell differentiation	J:79568
	decreased cytotoxic T cell cytolysis	J:79568
	decreased NK cell number	J:79568
	decreased NK T cell number	J:79568
	impaired natural killer cell mediated cytotoxicity	J:79568
	increased B cell number	J:79568
	increased B cell proliferation	J:79568
	increased hematopoietic stem cell number	J:107070
	increased T cell proliferation	J:79568
	large lymphoid organs	J:79568

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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