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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rassf1
Ras association (RalGDS/AF-6) domain family member 1
MGI:1928386
21 phenotypes from 3 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Rassf1tm1.1Brd/Rassf1tm1.1Brd
involves: 129S7/SvEvBrd * C57BL/6 		no abnormal phenotype detected J:101369
Rassf1tm1.1Brd/Rassf1tm1.1Brd
Tg(Myh6-cre)2182Mds/0
involves: 129S7/SvEvBrd * FVB/N 		decreased response of heart to induced stress J:165327
Rassf1tm1.2Brd/Rassf1tm1.2Brd
involves: 129S7/SvEvBrd 		cardiac fibrosis J:165327
cardiac hypertrophy J:165327
increased response of heart to induced stress J:165327
Rassf1tm1.2Brd/Rassf1tm1.2Brd
involves: 129S7/SvEvBrd * C57BL/6 		abnormal cell physiology J:101369
normal immune system phenotype J:101369
increased adenoma incidence J:101369
increased incidence of tumors by ionizing radiation induction J:101369
increased intestinal adenocarcinoma incidence J:101369
increased lymphoma incidence J:101369
increased mortality induced by ionizing radiation J:101369
premature death J:101369
Rassf1tm1Gpp/Rassf1+
involves: 129S1/SvImJ * C57BL/6 		increased incidence of tumors by chemical induction J:95683
increased lung adenoma incidence J:95683
Rassf1tm1Gpp/Rassf1tm1Gpp
involves: 129S1/SvImJ 		abnormal oval cell morphology J:231761
normal endocrine/exocrine gland phenotype J:231761
increased hepatocellular carcinoma incidence J:231761
increased liver adenoma incidence J:231761
increased liver tumor incidence J:231761
Rassf1tm1Gpp/Rassf1tm1Gpp
involves: 129S1/SvImJ * C57BL/6 		increased B cell derived lymphoma incidence J:95683
increased incidence of tumors by chemical induction J:95683
increased lung adenoma incidence J:95683
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory