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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pdcd10
programmed cell death 10
MGI:1928396
56 phenotypes from 5 alleles in 11 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Lyz2tm1(cre)Ifo/Lyz2+
Pdcd10tm1Wami/Pdcd10tm1Wami
involves: 129 * 129P2/OlaHsd * C57BL/6 		abnormal neutrophil morphology J:256076
abnormal neutrophil physiology J:256076
increased circulating creatinine level J:256076
renal tubular necrosis J:256076
Pdcd10tm1.1Kwhi/Pdcd10tm1.1Kwhi
involves: C57BL/6 		embryonic growth arrest J:173947
embryonic lethality between somite formation and embryo turning, complete penetrance J:173947
Pdcd10tm1.1Wami/Pdcd10tm1.1Wami
involves: 129 * C57BL/6 		abnormal vasculogenesis J:171969
anemia J:171969
decreased embryo size J:171969
embryonic lethality between somite formation and embryo turning, incomplete penetrance J:171969
embryonic lethality during organogenesis, complete penetrance J:171969
impaired hematopoiesis J:171969
myocardial trabeculae hypoplasia J:171969
pallor J:171969
thin myocardium J:171969
Pdcd10tm1Arte/Pdcd10tm1Arte
Tg(Cdh5-cre/ERT2)1Rha/0
involves: C57BL/6 		abnormal brain vasculature morphology J:177584
abnormal retina vasculature morphology J:177584
Pdcd10tm1Kwhi/Pdcd10tm1.1Kwhi
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/?
involves: C57BL/6 * CBA 		abnormal astrocyte morphology J:173947
abnormal brain vasculature morphology J:173947
abnormal pericyte morphology J:173947
CNS inflammation J:173947
postnatal lethality J:173947
Pdcd10tm1Kwhi/Pdcd10tm1Kwhi
Nfatc1tm1.1(cre)Bz/Nfatc1+
involves: 129S1/Sv * 129X1/SvJ 		abnormal cardiac jelly morphology J:238897
lethality throughout fetal growth and development, complete penetrance J:238897
thin myocardium J:238897
Pdcd10tm1Kwhi/Pdcd10tm1Kwhi
Tg(Nes-cre)1Kln/?
involves: C57BL/6 * SJL 		no abnormal phenotype detected J:173947
Pdcd10tm1Kwhi/Pdcd10tm1Kwhi
Tg(Tek-cre)1Ywa/?
involves: C57BL/6 * SJL 		abnormal cardinal vein morphology J:173947
normal cardiovascular system phenotype J:173947
embryonic lethality during organogenesis, complete penetrance J:173947
Pdcd10tm1Wami/Pdcd10tm1Wami
Emx1tm1(cre)Krj/Emx1+
involves: 129 * 129S2/SvPas * C57BL/6 		abnormal brain vasculature morphology J:170480
astrocytosis J:170480
increased brain size J:170480
increased hemangioma incidence J:170480
normal mortality/aging J:170480
Pdcd10tm1Wami/Pdcd10tm1Wami
Taglntm2(cre)Yec/Tagln+
involves: 129 * 129S6/SvEvTac * C57BL/6 		normal cardiovascular system phenotype J:171969
normal mortality/aging J:171969
Pdcd10tm1Wami/Pdcd10tm1Wami
Tg(GFAP-cre)25Mes/0
involves: 129 * C57BL/6 * FVB/N 		abnormal brain morphology J:170480
abnormal brain vasculature morphology J:170480
abnormal gait J:170480
abnormal vascular endothelial cell migration J:170480
astrocytosis J:170480
circling J:170480
decreased body weight J:170480
dilated brain ventricle J:170480
dilated vasculature J:170480
hydrocephaly J:170480
increased brain size J:170480
increased hemangioma incidence J:170480
postnatal growth retardation J:170480
postnatal lethality, incomplete penetrance J:170480
premature death J:170480
Pdcd10tm1Wami/Pdcd10tm1Wami
Tg(Nes-cre)1Kln/0
involves: 129 * C57BL/6 * SJL 		abnormal brain morphology J:170480
increased brain size J:170480
normal mortality/aging J:171969
postnatal lethality, complete penetrance J:170480
prenatal lethality, incomplete penetrance J:170480
Pdcd10tm1Wami/Pdcd10tm1Wami
Tg(Tek-cre)12Flv/0
involves: 129 * C3H * C57BL/6 		abnormal angiogenesis J:171969
abnormal brain vasculature morphology J:171969
abnormal cardinal vein morphology J:171969
abnormal developmental vascular remodeling J:171969
abnormal dorsal aorta morphology J:171969
abnormal endocardium morphology J:171969
abnormal intersomitic vessel morphology J:171969
abnormal myocardium layer morphology J:171969
abnormal vascular branching morphogenesis J:171969
abnormal vitelline vascular remodeling J:171969
abnormal vitelline vasculature morphology J:171969
anemia J:171969
dilated dorsal aorta J:171969
embryonic lethality during organogenesis, complete penetrance J:171969
enlarged pericardium J:171969
impaired hematopoiesis J:171969
microcephaly J:171969
myocardial trabeculae hypoplasia J:171969
normal nervous system phenotype J:171969
pallor J:171969
thin myocardium J:171969
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory