Kcnd3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kcnd3
potassium voltage-gated channel, Shal-related family, member 3
MGI:1928743

25 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kcnd3^em1(IMPC)J/Kcnd3^em1(IMPC)J C57BL/6NJ-Kcnd3^em1(IMPC)J/J	abnormal startle reflex	J:211773
	decreased blood urea nitrogen level	J:211773
	decreased exploration in new environment	J:211773
	decreased locomotor activity	J:211773
	decreased thigmotaxis	J:211773
	hyperactivity	J:211773
	increased bone mineral content	J:211773
	increased vertical activity	J:211773
Kcnd3^em1Tfts/Kcnd3^em1Tfts C57BL/6J-Kcnd3^em1Tfts	normal behavior/neurological phenotype	J:363793
	normal growth/size/body region phenotype	J:363793
	normal reproductive system phenotype	J:363793
Kcnd3^tm1Dgen/Kcnd3^tm1Dgen B6.Cg-Kcnd3^tm1Dgen	normal cardiovascular system phenotype	J:130722
Kcnd3^tm1Tfts/Kcnd3⁺ C57BL/6-Kcnd3^tm1Tfts	abnormal cerebellar Golgi cell morphology	J:363793
	abnormal gait	J:363793
	abnormal motor coordination/balance	J:363793
	abnormal Purkinje cell mitochondrial morphology	J:363793
	abnormal vesicle-mediated transport	J:363793
	ataxia	J:363793
	decreased locomotor activity	J:363793
	impaired coordination	J:363793
	impaired limb coordination	J:363793
	Purkinje cell degeneration	J:363793
	short stride length	J:363793
Kcnd3^tm1Tfts/Kcnd3^tm1Tfts C57BL/6-Kcnd3^tm1Tfts	abnormal cell nucleus morphology	J:363793
	abnormal cerebellar Golgi cell morphology	J:363793
	abnormal gait	J:363793
	abnormal motor coordination/balance	J:363793
	abnormal Purkinje cell mitochondrial morphology	J:363793
	abnormal vesicle-mediated transport	J:363793
	ataxia	J:363793
	dilated endoplasmic reticulum	J:363793
	impaired coordination	J:363793
	impaired limb coordination	J:363793
	increased locomotor activity	J:363793
	increased vertical activity	J:363793
	Purkinje cell degeneration	J:363793
	short stride length	J:363793

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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