Ruvbl1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ruvbl1
RuvB-like AAA ATPase 1
MGI:1928760

11 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ruvbl1^tm1.1Oxbk/Ruvbl1^tm1.1Oxbk Tg(Mx1-cre)1Cgn/0 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * CBA/J * SJL	abnormal definitive hematopoiesis	J:220926
	abnormal hematopoietic stem cell physiology	J:220926
	absent hematopoietic stem cells	J:220926
	bone marrow failure	J:220926
	decreased bone marrow cell number	J:220926
	pancytopenia	J:220926
	premature death	J:220926
Ruvbl1^tm1.2Oxbk/Ruvbl1^tm1.2Oxbk involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 * SJL	abnormal blastocyst formation	J:220926
	decreased inner cell mass proliferation	J:220926
	embryonic lethality before implantation, complete penetrance	J:220926
Ruvbl1^{tm1a(EUCOMM)Wtsi}/Ruvbl1⁺ C57BL/6N-Ruvbl1^{tm1a(EUCOMM)Wtsi}/Ics	decreased body weight	J:165965

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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