Pdzk1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pdzk1
PDZ domain containing 1
MGI:1928901

25 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pdzk1^tm1Dls/Pdzk1^tm1Dls involves: 129S6/SvEvTac * C57BL/6J	abnormal circulating protein level	J:107125
	abnormal liver morphology	J:107125
Pdzk1^tm1Oko/Pdzk1^tm1Oko either: (involves: 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)	increased circulating cholesterol level	J:81814
Pdzk1^{tm2b(EUCOMM)Wtsi}/Pdzk1⁺ C57BL/6N-Pdzk1^{tm2b(EUCOMM)Wtsi}/Wtsi	increased circulating cholesterol level	J:211773
	increased circulating HDL cholesterol level	J:211773
	increased circulating LDL cholesterol level	J:211773
Pdzk1^{tm2b(EUCOMM)Wtsi}/Pdzk1^{tm2b(EUCOMM)Wtsi} C57BL/6N-Pdzk1^{tm2b(EUCOMM)Wtsi}/Wtsi	abnormal eye muscle morphology	J:239583
	abnormal forebrain morphology	J:239583
	abnormal infrahyoid muscle connection	J:239583
	abnormal lymphatic vessel morphology	J:239583
	abnormal Mullerian duct morphology	J:239583
	abnormal vertebral artery topology	J:239583
	abnormal vitelline vein connection	J:239583
	abnormal Wolffian duct morphology	J:239583
	absent connection between subcutaneous lymph vessels and lymph sac	J:239583
	absent segment of posterior cerebral artery	J:239583
	anomalous pulmonary venous connection	J:239583
	atrioventricular septal defect	J:239583
	blood in lymph vessels	J:239583
	double lumen aortic arch	J:239583
	fusion of vertebral arches	J:239583
	ostium primum atrial septal defect	J:239583
	polydactyly	J:239583
	preweaning lethality, incomplete penetrance	J:211773
	subcutaneous edema	J:239583
	symmetric azygos veins	J:239583

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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