Rybp Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rybp
RING1 and YY1 binding protein
MGI:1929059

28 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gt(ROSA)26Sor^{tm1(Rybp/EGFP)Cve}/Gt(ROSA)26Sor⁺ Tmem163^{Tg(ACTB-cre)2Mrt}/0 involves: 129S1/Sv * 129X1/SvJ * FVB/N	cornea vascularization	J:134428
Gt(ROSA)26Sor^{tm1(Rybp/EGFP)Cve}/Gt(ROSA)26Sor⁺ Tg(Cryaa-cre)10Mlr/0 involves: 129S1/Sv * 129X1/SvJ	abnormal lens fiber morphology	J:134428
	cataract	J:134428
Gt(ROSA)26Sor^{tm1(Rybp/EGFP)Cve}/Gt(ROSA)26Sor^{tm1(Rybp/EGFP)Cve} Tmem163^{Tg(ACTB-cre)2Mrt}/0 involves: 129S1/Sv * 129X1/SvJ * FVB/N	abnormal vitreous body morphology	J:134428
	absent eye anterior chamber	J:134428
	cataract	J:134428
	coloboma	J:134428
	cornea vascularization	J:134428
	retina fold	J:134428
Rybp^em1(IMPC)Bay/Rybp⁺ C57BL/6N-Rybp^em1(IMPC)Bay/Bay	abnormal locomotor behavior	J:211773
Rybp^em1(IMPC)Bay/Rybp⁺ C57BL/6N-Rybp^em1(IMPC)Bay/Bay	decreased circulating alkaline phosphatase level	J:211773
Rybp^em1(IMPC)Bay/Rybp^em1(IMPC)Bay C57BL/6N-Rybp^em1(IMPC)Bay/Bay	preweaning lethality, complete penetrance	J:211773
Rybp^tm1Nisa/Rybp⁺ involves: 129S1/Sv * 129X1/SvJ	coloboma	J:134428
	optic nerve atrophy	J:134428
	optic nerve coloboma	J:134428
	retina coloboma	J:134428
	retina hyperplasia	J:134428
	ventral rotation of lens	J:134428
Rybp^tm1Nisa/Rybp⁺ involves: 129S1/Sv * 129X1/SvJ * ICR	abnormal forebrain development	J:134591
	abnormal midbrain development	J:134591
	delayed neural tube closure	J:134591
	exencephaly	J:134591
	neonatal lethality, incomplete penetrance	J:134591
Rybp^tm1Nisa/Rybp^tm1Nisa involves: 129S1/Sv * 129X1/SvJ * ICR	abnormal embryonic epiblast morphology	J:134591
	abnormal visceral endoderm morphology	J:134591
	absent trophectoderm	J:134591
	absent trophoblast giant cells	J:134591
	embryonic epiblast cell degeneration	J:134591
	embryonic growth retardation	J:134591
	embryonic lethality between implantation and somite formation, complete penetrance	J:134591
	impaired embryo implantation	J:134591

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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