About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rnf8
ring finger protein 8
MGI:1929069
43 phenotypes from 2 alleles in 1 genetic background
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Rnf8Gt(AS0574)Wtsi/Rnf8+
involves: 129P2/OlaHsd * C57BL/6 		abnormal class switch recombination J:161240
decreased body size J:161240
increased cellular sensitivity to gamma-irradiation J:161240
normal neoplasm J:161240
premature death J:161240
Rnf8Gt(AS0574)Wtsi/Rnf8Gt(AS0574)Wtsi
involves: 129P2/OlaHsd * C57BL/6 		abnormal class switch recombination J:161240
abnormal seminiferous tubule epithelium morphology J:161240
abnormal spermatocyte morphology J:161240
abnormal spermatogenesis J:161240
abnormal spermatogonia morphology J:161240
azoospermia J:161240
decreased B cell number J:161240
decreased body size J:161240
decreased body weight J:161240
decreased bone marrow cell number J:161240
decreased CD4-positive, alpha-beta T cell number J:161240
decreased CD8-positive, alpha-beta T cell number J:161240
decreased double-negative T cell number J:161240
decreased double-positive T cell number J:161240
decreased fibroblast proliferation J:161240
decreased IgG1 level J:161240
decreased IgG2b level J:161240
decreased IgG3 level J:161240
decreased immature B cell number J:161240
decreased litter size J:161240
decreased pre-B cell number J:161240
decreased pro-B cell number J:161240
decreased splenocyte number J:161240
decreased T cell number J:161240
decreased thymocyte number J:161240
increased cellular sensitivity to gamma-irradiation J:161240
increased lymphoma incidence J:161240
increased mammary adenocarcinoma incidence J:161240
increased mortality induced by gamma-irradiation J:161240
increased sarcoma incidence J:161240
increased skin tumor incidence J:161240
increased T cell derived lymphoma incidence J:161240
increased thymocyte apoptosis J:161240
induced chromosome breakage J:161240
oligozoospermia J:161240
postnatal growth retardation J:161240
premature death J:161240
reduced male fertility J:161240
seminiferous tubule degeneration J:161240
small testis J:161240
spontaneous chromosome breakage J:161240
Rnf8Gt(RRR260)Byg/Rnf8Gt(RRR260)Byg
involves: 129P2/OlaHsd * C57BL/6 		abnormal class switch recombination J:161240
abnormal seminiferous tubule epithelium morphology J:161240
abnormal spermatocyte morphology J:161240
abnormal spermatogenesis J:161240
abnormal spermatogonia morphology J:161240
azoospermia J:161240
decreased B cell number J:161240
decreased body size J:161240
decreased body weight J:161240
decreased bone marrow cell number J:161240
decreased CD4-positive, alpha-beta T cell number J:161240
decreased CD8-positive, alpha-beta T cell number J:161240
decreased double-negative T cell number J:161240
decreased double-positive T cell number J:161240
decreased fibroblast proliferation J:161240
decreased IgG1 level J:161240
decreased IgG2b level J:161240
decreased IgG3 level J:161240
decreased immature B cell number J:161240
decreased pre-B cell number J:161240
decreased pro-B cell number J:161240
decreased splenocyte number J:161240
decreased T cell number J:161240
decreased thymocyte number J:161240
increased cellular sensitivity to gamma-irradiation J:161240
increased lymphoma incidence J:161240
increased mammary adenocarcinoma incidence J:161240
increased mortality induced by gamma-irradiation J:161240
increased sarcoma incidence J:161240
increased skin tumor incidence J:161240
increased T cell derived lymphoma incidence J:161240
increased thymocyte apoptosis J:161240
induced chromosome breakage J:161240
male infertility J:161240
oligozoospermia J:161240
postnatal growth retardation J:161240
premature death J:161240
seminiferous tubule degeneration J:161240
small testis J:161240
spontaneous chromosome breakage J:161240
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory