Ptges3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ptges3
prostaglandin E synthase 3
MGI:1929282

22 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ptges3^{Gt(RST271)Byg}/Ptges3^{Gt(RST271)Byg} involves: 129P2/OlaHsd * C57BL/6	abnormal breathing pattern	J:117591
	abnormal epidermis stratum corneum morphology	J:117591
	abnormal skin appearance	J:117591
	abnormal surfactant secretion	J:117591
	atelectasis	J:117591
	decreased type II pneumocyte number	J:117591
	impaired lung alveolus development	J:117591
	impaired skin barrier function	J:117591
	lethargy	J:117591
	neonatal lethality, complete penetrance	J:117591
	pale lung	J:117591
	shiny skin	J:117591
	small lung	J:117591
Ptges3^{Gt(W069F07)Wrst}/Ptges3^{Gt(W069F07)Wrst} involves: 129X1/SvJ * C57BL/6	abnormal breathing pattern	J:117591
	abnormal skin appearance	J:117591
	abnormal surfactant secretion	J:117591
	atelectasis	J:117591
	decreased type II pneumocyte number	J:117591
	impaired lung alveolus development	J:117591
	impaired skin barrier function	J:117591
	lethargy	J:117591
	neonatal lethality, complete penetrance	J:117591
	pale lung	J:117591
	shiny skin	J:117591
	small lung	J:117591
Ptges3^tm1Nkt/Ptges3^tm1Nkt involves: 129P2/OlaHsd * C57BL/6	abnormal dermal layer morphology	J:125188
	abnormal epidermal layer morphology	J:125188
	abnormal epidermis stratum corneum morphology	J:125188
	atelectasis	J:125188
	decreased body weight	J:125188
	decreased fibroblast proliferation	J:125188
	decreased prostaglandin level	J:125188
	fetal growth retardation	J:125188
	perinatal lethality, complete penetrance	J:125188
	respiratory distress	J:125188
	thin epidermis	J:125188

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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