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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Cldn12
claudin 12
MGI:1929288
41 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Cldn12tm1.1(KOMP)Vlcg/Cldn12tm1.1(KOMP)Vlcg
B6J.B6N-Cldn12tm1.1(KOMP)Vlcg 		abnormal circulating non-HDL cholesterol level J:279934
abnormal heart echocardiography feature J:279934
abnormal motor coordination/balance J:279934
decreased anxiety-related response J:279934
decreased body length J:279934
decreased body mass index J:279934
decreased bone mineral content J:279934
decreased bone volume J:279934
decreased cardiac stroke volume J:279934
decreased circulating free fatty acids level J:279934
decreased circulating total protein level J:279934
decreased circulating triglyceride level J:279934
decreased erythrocyte cell number J:279934
decreased fasting circulating glucose level J:279934
decreased food intake J:279934
decreased locomotor activity J:279934
decreased respiratory quotient J:279934
decreased startle reflex J:279934
decreased total retina thickness J:279934
decreased vertical activity J:279934
normal immune system phenotype J:279934
increased alkaline phosphatase activity J:279934
increased body fat mass J:279934
increased body weight J:279934
increased cardiac muscle contractility J:279934
increased circulating creatinine level J:279934
increased circulating glucose level J:279934
increased leukocyte cell number J:279934
increased liver weight J:279934
increased mean corpuscular hemoglobin J:279934
increased or absent threshold for auditory brainstem response J:279934
increased spleen weight J:279934
macrocytosis J:279934
microphthalmia J:279934
normal nervous system phenotype J:279934
preweaning lethality, incomplete penetrance J:279934
shortened PQ interval J:279934
shortened PR interval J:279934
tremors J:279934
Cldn12tm1b(EUCOMM)Wtsi/Cldn12tm1b(EUCOMM)Wtsi
C57BL/6N-Cldn12tm1b(EUCOMM)Wtsi/Bay 		hyperactivity J:211773
increased grip strength J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory