Ndfip1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ndfip1
Nedd4 family interacting protein 1
MGI:1929601

26 phenotypes from 5 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ndfip1^{Gt(RRD002)Byg}/Ndfip1^{Gt(RRD002)Byg} involves: 129P2/OlaHsd	abnormal T cell physiology	J:205692
	increased activated T cell number	J:205692
	increased interleukin-2 secretion	J:205692
	increased T cell proliferation	J:205692
Ndfip1^{Gt(RRD002)Byg}/Ndfip1^{Gt(RRD002)Byg} involves: 129P2/OlaHsd * C57BL/6	abnormal bile duct morphology	J:116617
	abnormal bone marrow cell number	J:116617
	abnormal liver morphology	J:116617
	abnormal T cell physiology	J:116617
	abnormal T-helper 2 physiology	J:116617
	abnormal tail morphology	J:116617
	cachexia	J:116617
	dermatitis	J:116617
	extramedullary hematopoiesis	J:116617
	increased activated T cell number	J:116617
	increased inflammatory response	J:116617
	increased liver weight	J:116617
	increased spleen weight	J:116617
	increased T cell proliferation	J:116617
	lung inflammation	J:116617
	premature death	J:116617
	short tail	J:116617
Ndfip1^kru/Ndfip1^kru involves: C57BL/6JSfdAnu	normal immune system phenotype	J:188722
Ndfip1^kru/Ndfip1^kru involves: C57BL/6JSfdAnu	increased T-helper 2 cell number	J:188722
Ndfip1^tm1.1Pmo/Ndfip1^tm1.1Pmo Tg(Cd4-cre)1Cwi/0 involves: C57BL/6 * DBA/2	esophageal inflammation	J:205692
	increased activated T cell number	J:205692
	increased eosinophil cell number	J:205692
	skin inflammation	J:205692
Ndfip1^tm1.1Sest/Ndfip1^tm1.1Sest involves: C57BL/6	abnormal iron homeostasis	J:212711
Ndfip1^tm1.1Sest/Ndfip1^tm1.1Sest involves: C57BL/6	increased susceptibility to dopaminergic neuron neurotoxicity	J:212711
Ndfip1^tm1Sest/Ndfip1^tm1Sest Tg(Nes-cre)1Kln/0 involves: C57BL/6 * SJL	increased cerebral infarct size	J:180657

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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