Metap2 Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Metap2
methionine aminopeptidase 2
MGI:1929701

14 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Metap2^tm1.1Ccr/Metap2^tm1.1Ccr Tg(Tek-cre)12Flv/0 involves: 129S6/SvEvTac * C3H * C57BL/6	abnormal blood vessel morphology	J:111701
	abnormal dorsal aorta morphology	J:111701
	abnormal intersomitic vessel morphology	J:111701
	abnormal vascular development	J:111701
	decreased embryo size	J:111701
	decreased vascular endothelial cell number	J:111701
	disorganized embryonic tissue	J:111701
	embryo tissue necrosis	J:111701
	embryonic growth arrest	J:111701
	embryonic lethality during organogenesis, complete penetrance	J:111701
Metap2^tm1.2Ccr/Metap2^tm1.2Ccr involves: 129S6/SvEvTac * C57BL/6 * FVB/N	absent mesoderm	J:111701
	decreased cell proliferation	J:111701
	decreased embryo size	J:111701
	embryonic growth arrest	J:111701
	embryonic lethality between somite formation and embryo turning, complete penetrance	J:111701
	failure to gastrulate	J:111701

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24