Metap2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Metap2
methionine aminopeptidase 2
MGI:1929701

14 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Metap2^tm1.1Ccr/Metap2^tm1.1Ccr Tg(Tek-cre)12Flv/0 involves: 129S6/SvEvTac * C3H * C57BL/6	abnormal blood vessel morphology	J:111701
	abnormal dorsal aorta morphology	J:111701
	abnormal intersomitic vessel morphology	J:111701
	abnormal vascular development	J:111701
	decreased embryo size	J:111701
	decreased vascular endothelial cell number	J:111701
	disorganized embryonic tissue	J:111701
	embryo tissue necrosis	J:111701
	embryonic growth arrest	J:111701
	embryonic lethality during organogenesis, complete penetrance	J:111701
Metap2^tm1.2Ccr/Metap2^tm1.2Ccr involves: 129S6/SvEvTac * C57BL/6 * FVB/N	absent mesoderm	J:111701
	decreased cell proliferation	J:111701
	decreased embryo size	J:111701
	embryonic growth arrest	J:111701
	embryonic lethality between somite formation and embryo turning, complete penetrance	J:111701
	failure to gastrulate	J:111701

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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