Terf2ip Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Terf2ip
telomeric repeat binding factor 2, interacting protein
MGI:1929871

26 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Terf2ip^em1(IMPC)Mbp/Terf2ip^em1(IMPC)Mbp C57BL/6N-Terf2ip^em1(IMPC)Mbp/MbpMmucd	impaired glucose tolerance	J:211773
	scaly skin	J:211773
Terf2ip^Gt(XD108)Byg/Terf2ip⁺ involves: 129P2/OlaHsd * C57BL/6	decreased susceptibility to bacterial infection induced morbidity/mortality	J:163158
	decreased susceptibility to endotoxin shock	J:163158
Terf2ip^Gt(XD108)Byg/Terf2ip^Gt(XD108)Byg involves: 129P2/OlaHsd * C57BL/6	embryonic lethality, complete penetrance	J:163158
Terf2ip^tm1.1Blas/Terf2ip^tm1.1Blas involves: 129S2/SvPas * C57BL/6 * C57BL/6J * SJL	abnormal telomere morphology	J:165984
	normal cellular phenotype	J:165984
	decreased telomere length	J:165984
	increased chromosomal stability	J:165984
Terf2ip^tm1.1Blas/Terf2ip^tm1.1Blas Tg(KRT5-cre)1Tak/0 involves: 129S2/SvPas * C3H * C57BL/6 * SJL	abnormal telomere morphology	J:165984
	hyperpigmentation	J:165984
	increased body weight	J:165984
Terf2ip^tm1.2Tdl/Terf2ip^tm1.2Tdl involves: C57BL/6J * FVB/N	abnormal abdominal fat pad morphology	J:199372
	abnormal susceptibility to weight gain	J:199372
	normal cellular phenotype	J:158884, J:199372
	hepatic steatosis	J:199372
	normal homeostasis/metabolism phenotype	J:199372
	impaired glucose tolerance	J:199372
	increased abdominal adipose tissue amount	J:199372
	increased abdominal fat pad weight	J:199372
	increased cholesterol level	J:199372
	increased circulating glucose level	J:199372
	increased circulating insulin level	J:199372
	increased percent body fat/body weight	J:199372
	increased subcutaneous adipose tissue amount	J:199372
	insulin resistance	J:199372
	normal mortality/aging	J:199372
	obese	J:199372
	normal reproductive system phenotype	J:158884

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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