Akr1a1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Akr1a1
aldo-keto reductase family 1, member A1
MGI:1929955

17 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Akr1a1^{Gt(OST222400)Lex}/Akr1a1^{Gt(OST222400)Lex} B6.129S5-Akr1a1^{Gt(OST222400)Lex}	abnormal osteoblast differentiation	J:164548
	abnormal osteoblast physiology	J:164548
	abnormal osteoclast physiology	J:164548
	abnormal trabecular bone morphology	J:164548
	abnormal turbinate morphology	J:164548
	abnormal vitamin C level	J:164548
	aminoaciduria	J:164548
	decreased bone trabecula number	J:164548
	decreased bone volume	J:164548
	decreased compact bone thickness	J:164548
	decreased osteoblast cell number	J:164548
	decreased trabecular bone thickness	J:164548
	female infertility	J:164548
	fragile skeleton	J:164548
	increased osteoclast cell number	J:164548
	osteoporosis	J:164548
Akr1a1^tm1Maka/Akr1a1⁺ B6.Cg-Akr1a1^tm1Maka	abnormal enzyme/coenzyme activity	J:188043
Akr1a1^tm1Maka/Akr1a1^tm1Maka B6.Cg-Akr1a1^tm1Maka	abnormal enzyme/coenzyme activity	J:188043
Akr1a1^tm1Maka/Akr1a1^tm1Maka B6.Cg-Akr1a1^tm1Maka	abnormal vitamin C level	J:188043

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24