Klf15 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Klf15
Kruppel-like transcription factor 15
MGI:1929988

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apoe^tm1Unc/Apoe^tm1Unc Klf15^tm1Jain/Klf15^tm1Jain involves: 129P2/OlaHsd * 129X1/SvJ	increased circulating cholesterol level	J:203920
	increased circulating triglyceride level	J:203920
	increased susceptibility to atherosclerosis	J:203920
	increased susceptibility to induced morbidity/mortality	J:203920
Apoe^tm1Unc/Apoe^tm1Unc Klf15^tm2Jain/Klf15^tm2Jain Tg(Tagln-cre)1Jjl/0 involves: 129P2/OlaHsd * FVB/N	blood vessel inflammation	J:203920
	normal homeostasis/metabolism phenotype	J:203920
	increased macrophage cell number	J:203920
	increased susceptibility to atherosclerosis	J:203920
	vascular smooth muscle hypoplasia	J:203920
Klf15^tm1Jain/Klf15^tm1Jain Trp53^tm1Tyj/Trp53^tm1Tyj involves: 129S2/SvPas * 129X1/SvJ * C57BL/6	normal cardiovascular system phenotype	J:167880

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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