Ppp2r3c Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ppp2r3c
protein phosphatase 2, regulatory subunit B'', gamma
MGI:1930009

17 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ppp2r3c^em1(IMPC)H/Ppp2r3c^em1(IMPC)H C57BL/6NTac-Ppp2r3c^em1(IMPC)H/H	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Ppp2r3c^tm1Imku/Ppp2r3c^tm1Imku Tg(CD19-cre/ERT2)1Cgn/? involves: C57BL/6	abnormal B cell activation	J:100706
	abnormal humoral immune response	J:100706
	decreased B cell number	J:100706
	decreased B cell proliferation	J:100706
	decreased B-1a cell number	J:100706
	decreased follicular B cell number	J:100706
	decreased immature B cell number	J:100706
	decreased mature B cell number	J:100706
	decreased pre-B cell number	J:100706
	decreased spleen germinal center size	J:100706
	decreased transitional stage B cell number	J:100706
	increased pro-B cell number	J:100706
	increased T cell number	J:100706
	increased transitional stage B cell number	J:100706
	small spleen	J:100706

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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