Piwil2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Piwil2
piwi-like RNA-mediated gene silencing 2
MGI:1930036

12 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Piwil2^tm1.1Doca/Piwil2^tm1.1Doca involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J	abnormal cell physiology	J:184034
	abnormal DNA methylation	J:184034
	abnormal male germ cell apoptosis	J:184034
	arrest of male meiosis	J:184034
	male infertility	J:184034
	testicular atrophy	J:184034
Piwil2^tm1.1Doca/Piwil2^tm2.1Doca Tg(Stra8-icre)1Reb/0 involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * FVB/NJ	abnormal cell physiology	J:199259
	abnormal male germ cell apoptosis	J:199259
	decreased testis weight	J:199259
	male infertility	J:199259
Piwil2^tm1Nkn/Piwil2^tm1Nkn involves: 129S2/SvPas * C57BL/6	arrest of male meiosis	J:87735
	azoospermia	J:87735
	decreased testis weight	J:87735
	increased male germ cell apoptosis	J:87735
	male infertility	J:87735
	normal reproductive system phenotype	J:87735
Piwil2^tm1Nkn/Piwil2^tm1Nkn Tg(Piwil2)#Hsas/0 involves: 129S2/SvPas	normal reproductive system phenotype	J:192826
Piwil2^tm2.1Doca/Piwil2^tm2.1Doca Tg(Stra8-icre)1Reb/0 involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * FVB/NJ	abnormal cell physiology	J:199259
	abnormal male germ cell apoptosis	J:199259
	decreased testis weight	J:199259
	male infertility	J:199259
Piwil2^tm2.2Doca/Piwil2^tm2.2Doca involves: 129P2/OlaHsd * 129S4/SvJaeSor * BALB/cJ * C57BL/6J	abnormal cell physiology	J:199259
	abnormal spermatocyte morphology	J:199259
	abnormal spermatogonia morphology	J:199259

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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