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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Fads2
fatty acid desaturase 2
MGI:1930079
54 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Fads2tm1Mtna/Fads2tm1Mtna
involves: 129S6/SvEvTac * C57BL/6J 		abnormal acroplaxome morphology J:176697
abnormal acrosome assembly J:176697
abnormal Golgi apparatus morphology J:176697
abnormal proacrosomal vesicle fusion J:176697
abnormal spermatid morphology J:153293
abnormal spermatogenesis J:153293
abnormal spleen white pulp morphology J:153293
abnormal thymus cortex morphology J:153293
absent acrosome J:176697
arrest of spermiogenesis J:176697
azoospermia J:153293
decreased body weight J:153293
decreased food intake J:153293
decreased mature ovarian follicle number J:153293
dermatitis J:153293
enlarged kidney J:153293
enlarged liver J:153293
enlarged spleen J:153293
globozoospermia J:176697
impaired luteinization J:153293
impaired ovarian folliculogenesis J:153293
increased liver triglyceride level J:153293
increased liver weight J:153293
increased spleen red pulp amount J:153293
increased susceptibility to induced morbidity/mortality J:153293
increased susceptibility to weight loss J:153293
intestinal ulcer J:153293
lymphoid hypoplasia J:153293
male infertility J:153293
small thymus J:153293
spontaneous skin ulceration J:153293
Fads2tm1Wst/Fads2tm1Wst
involves: 129P2/OlaHsd 		abnormal gametogenesis J:140341
abnormal granulosa cell morphology J:140341
abnormal macrophage physiology J:140341
abnormal oocyte morphology J:140341
abnormal ovarian follicle morphology J:140341
abnormal platelet physiology J:140341
abnormal reproductive system physiology J:140341
abnormal Sertoli cell morphology J:140341
abnormal testis morphology J:140341
abnormal testis physiology J:140341
abnormal zona pellucida morphology J:140341
absent mature ovarian follicles J:140341
absent theca folliculi J:140341
absent zona pellucida J:140341
arrest of spermiogenesis J:140341
azoospermia J:140341
decreased platelet aggregation J:140341
decreased prostaglandin level J:140341
decreased susceptibility to induced thrombosis J:140341
decreased testis weight J:140341
decreased thromboxane level J:140341
decreased unsaturated fatty acids level J:140341
female infertility J:140341
normal homeostasis/metabolism phenotype J:140341
impaired ovarian folliculogenesis J:140341
increased bleeding time J:140341
male infertility J:140341
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory