Prdm15 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prdm15
PR domain containing 15
MGI:1930121

19 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prdm15^{tm1a(EUCOMM)Wtsi}/Prdm15⁺ involves: C57BL/6N	no abnormal phenotype detected	J:285408
Prdm15^{tm1a(EUCOMM)Wtsi}/Prdm15^{tm1a(EUCOMM)Wtsi} involves: C57BL/6N	abnormal anterior head development	J:285408
	abnormal brain morphology	J:285408
	abnormal embryonic neuroepithelium morphology	J:285408
	abnormal eye morphology	J:285408
	abnormal forebrain development	J:285408
	abnormal lateral ganglionic eminence morphology	J:285408
	abnormal medial ganglionic eminence morphology	J:285408
	abnormal rostral-caudal axis patterning	J:285408
	abnormal visceral yolk sac endoderm morphology	J:285408
	decreased embryo size	J:285408
	embryonic growth retardation	J:285408
	excessive folding of visceral yolk sac	J:285408
	holoprosencephaly	J:285408
	prenatal lethality, complete penetrance	J:285408
	rostral body truncation	J:285408
Prdm15^{tm1b(EUCOMM)Wtsi}/Prdm15⁺ C57BL/6N-Prdm15^{tm1b(EUCOMM)Wtsi}/BayMmucd	increased heart left ventricle size	J:211773
	thick ventricular wall	J:211773
Prdm15^{tm1b(EUCOMM)Wtsi}/Prdm15^{tm1b(EUCOMM)Wtsi} C57BL/6N-Prdm15^{tm1b(EUCOMM)Wtsi}/BayMmucd	preweaning lethality, incomplete penetrance	J:211773
Prdm15^{tm1c(EUCOMM)Wtsi}/Prdm15^{tm1c(EUCOMM)Wtsi} Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ involves: C57BL/6J * C57BL/6N	abnormal brain morphology	J:285408
	decreased embryo size	J:285408
	prenatal lethality, complete penetrance	J:285408
Prdm15^{tm1c(EUCOMM)Wtsi}/Prdm15^{tm1c(EUCOMM)Wtsi} Tg(Nes-cre)1Kln/0 involves: C57BL/6J * C57BL/6N	no abnormal phenotype detected	J:285408

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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