Pdcd1lg2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pdcd1lg2
programmed cell death 1 ligand 2
MGI:1930125

5 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cd274^tm1Shr/Cd274^tm1Shr Pdcd1lg2^tm3Shr/Pdcd1lg2^tm3Shr C.B6-Cd274^tm1Shr Pdcd1lg2^tm3Shr	abnormal dendritic cell physiology	J:123785
	decreased interleukin-4 secretion	J:123785
	increased interferon-gamma secretion	J:123785
	increased interleukin-2 secretion	J:123785
Cd274^tm2Shr/Cd274^tm2Shr Pdcd1lg2^tm4Shr/Pdcd1lg2^tm4Shr involves: 129S4/SvJae	abnormal immune system physiology	J:160970

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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