Tnk1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tnk1
tyrosine kinase, non-receptor, 1
MGI:1930958

18 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tnk1^{tm1b(EUCOMM)Hmgu}/Tnk1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Tnk1^{tm1b(EUCOMM)Hmgu}/J	decreased total body fat amount	J:211773
Tnk1^tm1Sksuf/Tnk1⁺ involves: 129X1/SvJ * C57BL/6	increased carcinoma incidence	J:140639
	increased hepatocellular carcinoma incidence	J:140639
	increased hepatoma incidence	J:140639
	increased intestinal adenocarcinoma incidence	J:140639
	increased intestinal adenoma incidence	J:140639
	increased lung adenoma incidence	J:140639
	increased lymphoma incidence	J:140639
	increased malignant tumor incidence	J:140639
	increased pancreas tumor incidence	J:140639
	increased skin tumor incidence	J:140639
	increased trichoepithelioma incidence	J:140639
	increased tumor incidence	J:140639
	pancreatic islet hyperplasia	J:140639
Tnk1^tm1Sksuf/Tnk1^tm1Sksuf involves: 129X1/SvJ * C57BL/6	increased B cell derived lymphoma incidence	J:140639
	increased gastrointestinal tumor incidence	J:140639
	increased hemangiosarcoma incidence	J:140639
	increased hepatocellular carcinoma incidence	J:140639
	increased lung adenocarcinoma incidence	J:140639
	increased lymphoma incidence	J:140639
	increased skin tumor incidence	J:140639
	increased trichoepithelioma incidence	J:140639
	increased tumor incidence	J:140639

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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