Thap11 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Thap11
THAP domain containing 11
MGI:1930964

25 phenotypes from 3 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Thap11^em1Poche/Thap11^em1Poche C57BL/6J-Thap11^em1Poche	abnormal astrocyte morphology	J:317822
	abnormal craniofacial development	J:317822
	abnormal craniofacial morphology	J:317822
	abnormal enzyme/coenzyme activity	J:317822
	abnormal enzyme/coenzyme level	J:317822
	abnormal trabecula carnea morphology	J:317822
	abnormal ventricle myocardium morphology	J:317822
	cyanosis	J:317822
	decreased embryo size	J:317822
	decreased erythrocyte cell number	J:317822
	decreased hematocrit	J:317822
	decreased hemoglobin content	J:317822
	enlarged lateral ventricles	J:317822
	exencephaly	J:317822
	kinked tail	J:317822
	neonatal lethality, complete penetrance	J:317822
	respiratory failure	J:317822
	thin cerebral cortex	J:317822
	thrombocytopenia	J:317822
	vertebral transformation	J:317822
Thap11^tm1.1Tpz/Thap11^tm1.1Tpz involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal cell physiology	J:136306
	absent inner cell mass proliferation	J:136306
	embryonic lethality between implantation and somite formation, complete penetrance	J:136306
Thap11^tm1Tpz/Thap11^em1Poche E2f1^{Tg(Wnt1-cre)2Sor}/E2f1⁺ involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J	belly spot	J:317822
	decreased digit pigmentation	J:317822
Thap11^tm1Tpz/Thap11^tm1Tpz involves: 129S1/Sv * 129X1/SvJ	abnormal cell physiology	J:136306
Thap11^tm1Tpz/Thap11^tm1Tpz E2f1^{Tg(Wnt1-cre)2Sor}/E2f1⁺ involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C3H * C57BL/6	abnormal craniofacial development	J:317822
Thap11^tm1Tpz/Thap11^tm1Tpz Tg(Prrx1-cre)1Cjt/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J	abnormal craniofacial development	J:317822

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24