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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sertad2
SERTA domain containing 2
MGI:1931026
29 phenotypes from 1 allele in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Sertad2Gt(OST98734)Lex/Sertad2+
B6.129S5-Sertad2Gt(OST98734)Lex 		decreased circulating cholesterol level J:194928
decreased circulating leptin level J:194928
Sertad2Gt(OST98734)Lex/Sertad2Gt(OST98734)Lex
B6.129S5-Sertad2Gt(OST98734)Lex 		abnormal circulating hormone level J:194928
abnormal glucose homeostasis J:194928
abnormal hormone level J:194928
abnormal lipid homeostasis J:194928
abnormal macrophage physiology J:194928
decreased body weight J:194928
decreased brown adipose tissue mass J:194928
decreased brown fat cell size J:194928
decreased circulating cholesterol level J:194928
decreased circulating glucose level J:194928
decreased circulating insulin level J:194928
decreased circulating leptin level J:194928
decreased epididymal fat pad weight J:194928
decreased liver triglyceride level J:194928
decreased liver weight J:194928
decreased percent body fat/body weight J:194928
decreased subcutaneous adipose tissue amount J:194928
decreased susceptibility to diet-induced hepatic steatosis J:194928
decreased susceptibility to diet-induced obesity J:194928
decreased white fat cell size J:194928
enhanced lipolysis J:194928
improved glucose tolerance J:194928
increased adiponectin level J:194928
increased brown fat cell number J:194928
increased core body temperature J:194928
increased insulin sensitivity J:194928
increased lean body mass J:194928
increased oxygen consumption J:194928
Sertad2Gt(OST98734)Lex/Sertad2Gt(OST98734)Lex
involves: 129S5/SvEvBrd 		decreased body weight J:194928
decreased fibroblast proliferation J:196054
decreased susceptibility to diet-induced obesity J:194928
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory