Recql4 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Recql4
RecQ protein-like 4
MGI:1931028

34 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Recql4^{tm1.1(KOMP)Vlcg}/Recql4⁺ C57BL/6N-Recql4^{tm1.1(KOMP)Vlcg}/Ucd	abnormal coat/ hair morphology	J:211773
	decreased body length	J:211773
	increased aggression	J:211773
Recql4^{tm1.1(KOMP)Vlcg}/Recql4^{tm1.1(KOMP)Vlcg} C57BL/6N-Recql4^{tm1.1(KOMP)Vlcg}/MbpMmucd	embryonic lethality prior to organogenesis	J:211773
Recql4^{tm1.1(KOMP)Vlcg}/Recql4^{tm1.1(KOMP)Vlcg} C57BL/6N-Recql4^{tm1.1(KOMP)Vlcg}/Ucd	preweaning lethality, complete penetrance	J:211773
Recql4^tm1Abe/Recql4^tm1Abe involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal long bone metaphysis morphology	J:85574
	abnormal small intestine morphology	J:85574
	abnormal thymus corticomedullary boundary morphology	J:85574
	absent coat pigmentation	J:85574
	alopecia	J:85574
	decreased body size	J:85574
	decreased body weight	J:85574
	decreased spleen white pulp amount	J:85574
	growth retardation of incisors	J:85574
	growth retardation of molars	J:85574
	neonatal lethality, incomplete penetrance	J:85574
	postnatal growth retardation	J:85574
	postnatal lethality, incomplete penetrance	J:85574
	skin lesions	J:85574
	small thymus	J:85574
	normal vision/eye phenotype	J:85574
Recql4^tm1Furu/Recql4^tm1Furu Not Specified	abnormal trophoblast giant cell morphology	J:85891
	decreased inner cell mass proliferation	J:85891
	embryonic lethality, complete penetrance	J:85891
Recql4^tm1Glu/Recql4^tm1Glu involves: 129S7/SvEvBrd * C57BL/6J	abnormal limb bone morphology	J:97101
	abnormal tail pigmentation	J:97101
	chromosome breakage	J:97101
	cleft palate	J:97101
	increased lymphoma incidence	J:97101
	increased sarcoma incidence	J:97101
	neonatal lethality, incomplete penetrance	J:97101
	polyphalangy	J:97101
	preaxial polydactyly	J:97101
	premature death	J:97101
	short forelimb	J:97101

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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