Noc2l Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Noc2l
NOC2 like nucleolar associated transcriptional repressor
MGI:1931051

23 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Noc2l^tm1.1Arte/Noc2l^tm1.1Arte Tg(CD2-icre)4Kio/0 involves: C57BL/6 * C57BL/10 * CBA/Ca	abnormal B cell morphology	J:216490
	abnormal cell cycle	J:216490
	abnormal T cell morphology	J:216490
	abnormal T cell proliferation	J:216490
	abnormal thymus cell ratio	J:216490
	abnormal thymus involution	J:216490
	abnormal thymus morphology	J:216490
	absent T cells	J:216490
	arrested T cell differentiation	J:216490
	decreased alpha-beta T cell number	J:216490
	decreased DN3 thymocyte number	J:216490
	decreased DN4 thymocyte number	J:216490
	decreased double-positive T cell number	J:216490
	decreased immature B cell number	J:216490
	decreased mature B cell number	J:216490
	decreased pre-B cell number	J:216490
	decreased pro-B cell number	J:216490
	decreased single-positive T cell number	J:216490
	increased thymocyte apoptosis	J:216490
	small thymus	J:216490
	spleen hypoplasia	J:216490
	thymus hypoplasia	J:216490
Noc2l^tm1.1Arte/Noc2l^tm1.2Arte Tmem163^{Tg(ACTB-cre)2Mrt}/0 involves: FVB/N	embryonic lethality prior to tooth bud stage, complete penetrance	J:216490

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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