Cubn Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cubn
cubilin
MGI:1931256

22 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cubn^{tm1b(EUCOMM)Hmgu}/Cubn⁺ C57BL/6N-Cubn^{tm1b(EUCOMM)Hmgu}/Bay	abnormal iris morphology	J:211773
	fused cornea and lens	J:211773
	iris synechia	J:211773
Cubn^{tm1b(EUCOMM)Hmgu}/Cubn^{tm1b(EUCOMM)Hmgu} C57BL/6N-Cubn^{tm1b(EUCOMM)Hmgu}/Bay	preweaning lethality, complete penetrance	J:211773
Cubn^tm1Rkoz/Cubn^tm1Rkoz Meox2^tm1(cre)Sor/Meox2⁺ involves: 129S4/SvJaeSor * 129X1/SvJ * C57BL/6	abnormal renal reabsorption	J:164025
	abnormal vitamin B12 level	J:164025
	albuminuria	J:164025
	postnatal lethality, incomplete penetrance	J:164025
Cubn^tm1Sarg/Cubn⁺ involves: 129/Sv * C57BL/6	premature death	J:119685
Cubn^tm1Sarg/Cubn^tm1Sarg involves: 129/Sv * C57BL/6	abnormal allantois morphology	J:119685
	abnormal embryonic tissue morphology	J:119685
	abnormal endoderm development	J:119685
	abnormal visceral endoderm morphology	J:119685
	abnormal vitelline vascular remodeling	J:119685
	abnormal vitelline vasculature morphology	J:119685
	absent allantois	J:119685
	absent amnion	J:119685
	absent chorion	J:119685
	absent somites	J:119685
	decreased embryo size	J:119685
	embryonic lethality during organogenesis, complete penetrance	J:119685
	failure of initiation of embryo turning	J:119685

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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