Pycard Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pycard
PYD and CARD domain containing
MGI:1931465

10 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Gt(ROSA)26Sor^{tm1(OVAL/fla,GFP)Vnce}/Gt(ROSA)26Sor⁺ Lyz2^tm1(cre)Ifo/Lyz2⁺ Pycard^tm1Vmd/Pycard^tm1Vmd involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	normal growth/size/body region phenotype	J:260047
	normal immune system phenotype	J:260047
	increased circulating interferon-gamma level	J:260047
	increased circulating interleukin-6 level	J:260047
	increased circulating tumor necrosis factor level	J:260047
Mefv^{tm5.1(MEFV)Chae}/Mefv^{tm5.1(MEFV)Chae} Pycard^tm1Tno/Pycard^tm1Tno involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6	decreased interleukin-1 beta secretion	J:172117
	normal growth/size/body region phenotype	J:172117
	normal immune system phenotype	J:172117
Nlrp1a^Neut1/Nlrp1a^Neut1 Pycard^tm1Vmd/Pycard^tm1Vmd involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal inflammatory response	J:191055
	increased neutrophil cell number	J:191055
Nlrp3^tm1Hhf/Nlrp3⁺ Pycard^tm1Flv/Pycard^tm1Flv Lyz2^tm1(cre)Ifo/Lyz2⁺ involves: 129 * C57BL/6	no abnormal phenotype detected	J:150054
Pycard^tm1Flv/Pycard^tm1Flv Slc11a1^s/Slc11a1^s B6.129S5-Pycard^tm1Flv	increased susceptibility to bacterial infection	J:124378

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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