Nfkbiz Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nfkbiz
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
MGI:1931595

47 phenotypes from 3 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd79a^tm1(cre)Reth/Cd79a⁺ Nfkbiz^tm1.1Muta/Nfkbiz^tm1.1Muta involves: BALB/c * C57BL/6	normal immune system phenotype	J:194832
Lyz2^tm1(cre)Ifo/Lyz2⁺ Nfkbiz^tm1.1Muta/Nfkbiz^tm1.1Muta involves: 129P2/OlaHsd * C57BL/6	normal immune system phenotype	J:194832
Nfkbiz^tm1.1Muta/Nfkbiz^tm1.1Muta Tg(CAG-cre)13Miya/? involves: C57BL/6	dermatitis	J:194832
	eyelid edema	J:194832
Nfkbiz^tm1.1Muta/Nfkbiz^tm1.1Muta Tg(KRT5-cre)1Tak/? involves: C3H * C57BL/6	dermatitis	J:194832
	increased lacrimal gland apoptosis	J:194832
Nfkbiz^tm1.1Muta/Nfkbiz^tm1.1Muta Tg(Lck-cre)1Jtak/? involves: C57BL/6	normal immune system phenotype	J:194832
Nfkbiz^tm1Aki/Nfkbiz^tm1Aki C.129P2-Nfkbiz^tm1Aki	abnormal epidermal layer morphology	J:141704
	abnormal hair growth	J:141704
	alopecia	J:141704
	blepharitis	J:141704
	conjunctivitis	J:141704
	decreased conjunctiva goblet cell number	J:141704
	dermatitis	J:141704
	epidermal hyperplasia	J:141704
	eye inflammation	J:141704
	increased IgE level	J:141704
	perioral dermatitis	J:141704
	prenatal lethality, incomplete penetrance	J:141704
	reddish skin	J:141704
	skin edema	J:141704
	skin inflammation	J:141704
Nfkbiz^tm1Aki/Nfkbiz^tm1Aki involves: 129P2/OlaHsd	abnormal conjunctiva goblet cell morphology	J:91297
	abnormal cytokine secretion	J:91297
	abnormal immune system organ morphology	J:194832
	abnormal immune system physiology	J:194832
	abnormal leukocyte physiology	J:91297
	abnormal lymph node cell ratio	J:194832
	abnormal lymphocyte morphology	J:194832
	abnormal T-helper 1 cell morphology	J:194832
	abnormal tumor necrosis factor secretion	J:91297
	blepharitis	J:96363
	conjunctivitis	J:96363
	corneal limbitis	J:96363
	decreased conjunctiva goblet cell number	J:96363
	decreased interleukin-6 secretion	J:91297
	decreased interleukin-12 secretion	J:91297
	decreased tear production	J:194832
	dermatitis	J:91297, J:194832
	enlarged lymph nodes	J:194832
	enlarged spleen	J:194832
	eye inflammation	J:96363
	eyelid edema	J:194832
	increased immunoglobulin level	J:194832
	increased lacrimal gland apoptosis	J:194832
	interstitial pneumonia	J:194832
	lacrimal gland inflammation	J:194832
	periocular dermatitis	J:194832
	skin lesions	J:96363
Nfkbiz^tm1Mamo/Nfkbiz^tm1Mamo involves: 129S7/SvEvBrd	abnormal skin condition	J:95040
	abnormal skin morphology	J:95040
	acanthosis	J:95040
	alopecia	J:95040
	dermatitis	J:95040
	excessive scratching	J:95040
	eyelid edema	J:95040
	hyperkeratosis	J:95040
	increased IgE level	J:95040
	parakeratosis	J:95040
	prenatal lethality, incomplete penetrance	J:95040
	scaly skin	J:95040
	spontaneous skin ulceration	J:95040
	thick skin	J:95040

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