Pum1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pum1
pumilio RNA-binding family member 1
MGI:1931749

12 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pum1^em1(IMPC)Mbp/Pum1^em1(IMPC)Mbp C57BL/6NCrl-Pum1^em1(IMPC)Mbp/MbpMmucd	abnormal skin morphology	J:211773
	decreased prepulse inhibition	J:211773
Pum1^Gt(XE002)Byg/Pum1^Gt(XE002)Byg B6.129P2-Pum1^Gt(XE002)Byg	embryonic lethality before implantation, complete penetrance	J:226959
Pum1^tm1.1Hfl/Pum1^tm1.2Hfl Tg(Ddx4-cre)1Dcas/0 involves: 129 * C57BL/6 * FVB	increased male germ cell apoptosis	J:182280
Pum1^tm1.2Hfl/Pum1⁺ involves: 129 * C57BL/6 * FVB	increased male germ cell apoptosis	J:182280
Pum1^tm1.2Hfl/Pum1⁺ involves: 129 * C57BL/6 * FVB	oligozoospermia	J:182280
Pum1^tm1.2Hfl/Pum1^tm1.2Hfl involves: 129 * C57BL/6 * FVB	abnormal spermatogenesis	J:182280
	decreased body weight	J:182280
	decreased testis weight	J:182280
	increased male germ cell apoptosis	J:182280
	oligozoospermia	J:182280
	reduced male fertility	J:182280
	normal reproductive system phenotype	J:182280
	small seminiferous tubules	J:182280
	testis hypoplasia	J:182280

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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