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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Agpat1
1-acylglycerol-3-phosphate O-acyltransferase 1
MGI:1932075
42 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Agpat1em1Andm/Agpat1em1Andm
C57BL/6J-Agpat1em1Andm 		decreased body size J:338850
postnatal lethality, complete penetrance J:338850
Agpat1tm1.1(KOMP)Vlcg/Agpat1+
B6N(Cg)-Agpat1tm1.1(KOMP)Vlcg/J 		decreased circulating calcium level J:211773
decreased circulating chloride level J:211773
decreased circulating glucose level J:211773
increased circulating alanine transaminase level J:211773
increased circulating alkaline phosphatase level J:211773
increased circulating potassium level J:211773
increased mean corpuscular hemoglobin J:211773
increased urine glucose level J:211773
increased urine microalbumin level J:211773
prolonged RR interval J:211773
Agpat1tm1.1(KOMP)Vlcg/Agpat1tm1.1(KOMP)Vlcg
B6N(Cg)-Agpat1tm1.1(KOMP)Vlcg/J 		preweaning lethality, incomplete penetrance J:211773
Agpat1tm1Garg/Agpat1tm1Garg
involves: 129S6/SvEvTac * C57BL/6 		abnormal enzyme/coenzyme activity J:250301
abnormal epididymal fat pad morphology J:250301
abnormal estrous cycle J:250301
abnormal hippocampus morphology J:250301
abnormal spermatid morphology J:250301
abnormal spermatocyte morphology J:250301
abnormal spermatogenesis J:250301
arrest of male meiosis J:250301
audiogenic seizures J:250301
normal behavior/neurological phenotype J:250301
decreased body weight J:250301
decreased circulating glucose level J:250301
decreased circulating insulin-like growth factor I level J:250301
decreased circulating leptin level J:250301
decreased ovulation rate J:250301
decreased percent body fat/body weight J:250301
female infertility J:250301
normal homeostasis/metabolism phenotype J:250301
hypoglycemia J:250301
impaired gluconeogenesis J:250301
increased circulating follicle stimulating hormone level J:250301
increased circulating luteinizing hormone level J:250301
increased locomotor activity J:250301
increased tertiary ovarian follicle number J:250301
increased vertical activity J:250301
male infertility J:250301
postnatal lethality, incomplete penetrance J:250301
premature death J:250301
prolonged diestrus J:250301
slow postnatal weight gain J:250301
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory