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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Klb
klotho beta
MGI:1932466
25 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Klbtm1.2Sakl/Klb+
Tg(Apoe-Fgf21)1Sakl/0
involves: 129 * 129S4/SvJaeSor * C57BL/6 		abnormal eating behavior J:189018
decreased body weight J:189018
decreased circulating cholesterol level J:189018
decreased circulating free fatty acids level J:189018
decreased circulating glucose level J:189018
decreased circulating insulin level J:189018
decreased circulating leptin level J:189018
decreased circulating triglyceride level J:189018
decreased liver cholesterol level J:189018
decreased liver triglyceride level J:189018
decreased liver weight J:189018
decreased percent body fat/body weight J:189018
decreased susceptibility to diet-induced hepatic steatosis J:189018
decreased susceptibility to weight gain J:189018
improved glucose tolerance J:189018
increased circulating adiponectin level J:189018
increased insulin sensitivity J:189018
increased lean body mass J:189018
short tibia J:189018
Klbtm1.2Sakl/Klbtm1.2Sakl
Tg(Apoe-Fgf21)1Sakl/0
involves: 129 * 129S4/SvJaeSor * C57BL/6 		abnormal blood homeostasis J:189018
abnormal food intake J:189018
abnormal glucose homeostasis J:189018
abnormal lean body mass J:189018
abnormal liver morphology J:189018
abnormal percent body fat/body weight J:189018
decreased body weight J:189018
decreased circulating free fatty acids level J:189018
short tibia J:189018
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory