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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sp6
trans-acting transcription factor 6
MGI:1932575
42 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Sp6tm1.1Ibmm/Sp6tm1.1Ibmm
involves: 129P2/OlaHsd * 129S4/SvJaeSor * BALB/c * C57BL/6 * CD-1 		abnormal ameloblast morphology J:132771
abnormal dentin morphology J:132771
abnormal enamel organ morphology J:132771
abnormal hair cuticle J:132771
abnormal hair follicle inner root sheath morphology J:132771
abnormal hair shaft morphology J:132771
abnormal Hertwig epithelial root sheath morphology J:132771
abnormal incisor morphology J:132771
abnormal molar cusp morphology J:132771
abnormal pulmonary alveolus morphology J:132771
abnormal tooth color J:132771
abnormal tooth development J:132771
abnormal tooth hard tissue morphology J:132771
abnormal tooth morphology J:132771
absent enamel J:132771
absent vibrissae J:132771
brittle teeth J:132771
curly vibrissae J:132771
decreased body weight J:132771
disorganized inner root sheath cells J:132771
enlarged sebaceous gland J:132771
fused molars J:132771
fused teeth J:132771
hairless J:132771
microdontia J:132771
oligodactyly J:132771
reduced enamel thickness J:132771
short tooth root J:132771
short vibrissae J:132771
small incisors J:132771
supernumerary molars J:132771
supernumerary teeth J:132771
syndactyly J:132771
thick epidermis J:132771
wrinkled skin J:132771
Sp6tm1Ibmm/Sp6+
involves: 129P2/OlaHsd * 129S4/SvJaeSor * CD-1 		no abnormal phenotype detected J:132771
Sp6tm1Yoya/Sp6tm1Yoya
B6.129-Sp6tm1Yoya 		abnormal dentin morphology J:132157
abnormal molar cusp morphology J:132157
abnormal tooth development J:132157
abnormal tooth mineralization J:132157
absent enamel J:132157
decreased body size J:132157
decreased survivor rate J:132157
delayed tooth eruption J:132157
premature death J:132157
supernumerary incisors J:132157
supernumerary teeth J:132157
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory