Akap12 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Akap12
A kinase anchor protein 12
MGI:1932576

24 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Akap12^{Gt(ble-lacZ)15Brr}/Akap12^{Gt(ble-lacZ)15Brr} involves: 129S2/SvPas	no abnormal phenotype detected	J:70587
Akap12^Gt(XE450)Byg/Akap12^Gt(XE450)Byg involves: 129P2/OlaHsd * C57BL/6	abnormal heart left ventricle morphology	J:207542
	abnormal heart septum morphology	J:207542
	abnormal myocardial fiber morphology	J:207542
	abnormal myocardial fiber physiology	J:207542
	increased cardiac stroke volume	J:207542
	increased heart left ventricle muscle contractility	J:207542
Akap12^tm1Ihg/Akap12^tm1Ihg involves: 129S4/SvJae * C57BL/6	abnormal cerebellar Purkinje cell layer	J:138882
	abnormal lung morphology	J:138882
	abnormal prostate gland morphology	J:138882
	abnormal prostate gland physiology	J:138882
	normal behavior/neurological phenotype	J:138882
	delayed female fertility	J:138882
	delayed fertility	J:138882
	delayed male fertility	J:138882
	enlarged heart	J:138882
	increased prostate gland weight	J:138882
	increased spleen red pulp amount	J:138882
	infertility	J:138882
	limb grasping	J:138882
	liver inflammation	J:138882
	premature death	J:138882
	prostate gland anterior lobe hyperplasia	J:138882
	prostate gland ventral lobe hyperplasia	J:138882

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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