Slc26a5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc26a5
solute carrier family 26, member 5
MGI:1933154

26 phenotypes from 6 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slc26a5^mpc234H/Slc26a5^mpc234H involves: BALB/c * C3H/HeH * C57BL/6J	deafness	J:234901
Slc26a5^tm1Jnz/Slc26a5⁺ involves: 129S7/SvEvBrd * C57BL/6J	abnormal cochlear outer hair cell morphology	J:79029
	abnormal distortion product otoacoustic emission	J:79029, J:118929
	cochlear inner hair cell degeneration	J:79029
	cochlear outer hair cell degeneration	J:79029
	decreased body weight	J:79029
	decreased cochlear outer hair cell electromotility	J:79029
	impaired hearing	J:79029, J:118929
	increased or absent threshold for auditory brainstem response	J:79029, J:91680
Slc26a5^tm1Jnz/Slc26a5^tm1Jnz involves: 129S7/SvEvBrd	abnormal cochlear outer hair cell morphology	J:145297
	abnormal otoacoustic response	J:160851
	increased cochlear nerve compound action potential	J:145297
Slc26a5^tm1Jnz/Slc26a5^tm1Jnz involves: 129S7/SvEvBrd * C57BL/6J	abnormal Claudius cell morphology	J:91680
	abnormal distortion product otoacoustic emission	J:79029, J:124148
	absent cochlear microphonics	J:79029
	absent cochlear outer hair cell electromotility	J:79029
	absent distortion product otoacoustic emissions	J:124148
	cochlear ganglion degeneration	J:91680
	cochlear hair cell degeneration	J:91680
	cochlear inner hair cell degeneration	J:79029, J:91680
	cochlear outer hair cell degeneration	J:79029, J:91680
	deafness	J:91680
	decreased body weight	J:79029
	decreased cochlear microphonics	J:105502, J:124148
	decreased cochlear nerve compound action potential	J:105502, J:124148
	degeneration of organ of Corti supporting cells	J:91680
	impaired hearing	J:79029
	increased or absent threshold for auditory brainstem response	J:79029, J:91680
	organ of Corti degeneration	J:91680
	short cochlear outer hair cells	J:79029, J:91680
Slc26a5^tm2Jnz/Slc26a5^tm2Jnz involves: 129S6/SvEvTac * FVB/N	abnormal cochlear outer hair cell electromotility	J:123299
Slc26a5^tm3Jnz/Slc26a5^tm3Jnz involves: 129S6/SvEvTac * C57BL/6 * FVB/N	abnormal cochlear outer hair cell physiology	J:145297
	decreased cochlear outer hair cell electromotility	J:145297
	decreased cochlear outer hair cell number	J:145297
	increased cochlear nerve compound action potential	J:145297
Slc26a5^{tm4(cre/ERT2)Jnz}/Slc26a5⁺ involves: 129S6/SvEvTac	normal hearing/vestibular/ear phenotype	J:182720
Slc26a5^{tm4.1(cre/ERT2)Jnz}/Slc26a5⁺ involves: 129S6/SvEvTac * C57BL/6	normal hearing/vestibular/ear phenotype	J:182720
Slc26a5^{tm4.1(cre/ERT2)Jnz}/Slc26a5^{tm4.1(cre/ERT2)Jnz} involves: 129S6/SvEvTac * C57BL/6	increased or absent threshold for auditory brainstem response	J:182720

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