Pik3ap1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pik3ap1
phosphoinositide-3-kinase adaptor protein 1
MGI:1933177

22 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pik3ap1^m1Btlr/Pik3ap1^m1Btlr involves: C57BL/6J	arrested B cell differentiation	J:185495
	decreased IgM level	J:185495
	normal immune system phenotype	J:185495
Pik3ap1^m2Btlr/Pik3ap1^m2Btlr C57BL/6J-Pik3ap1^m2Btlr	decreased B-1a cell number	J:255271
	impaired humoral immune response	J:255271
	increased B-1b cell number	J:255271
	increased IgM level	J:255271
Pik3ap1^M3Btlr/Pik3ap1^M3Btlr C57BL/6J-Pik3ap1^M3Btlr	decreased B-1 B cell number	J:272019
Pik3ap1^{tm1b(KOMP)Wtsi}/Pik3ap1^{tm1b(KOMP)Wtsi} C57BL/6N-Pik3ap1^{tm1b(KOMP)Wtsi}/Orl	abnormal cholesterol homeostasis	J:211773
	decreased lymphocyte cell number	J:211773
	increased monocyte cell number	J:211773
	increased neutrophil cell number	J:211773
Pik3ap1^tm1Kuro/Pik3ap1^tm1Kuro involves: 129P2/OlaHsd	abnormal B cell differentiation	J:75075
	absent B-1a cells	J:84669
	decreased B cell number	J:84669
	decreased B cell proliferation	J:84669
	decreased follicular B cell number	J:84669
	decreased IgG2b level	J:75075
	decreased IgG3 level	J:75075
	decreased IgM level	J:75075
	decreased immunoglobulin level	J:75075
	decreased pre-B cell number	J:75075
	spleen hypoplasia	J:75075

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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