Jam2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Jam2
junction adhesion molecule 2
MGI:1933820

13 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Jam2^{tm1.1(cre)Jrs}/Jam2^{tm1.1(cre)Jrs} involves: 129X1/SvJ * C57BL/6 * CD-1	abnormal dendrite morphology	J:254378
Jam2^{tm1.1(KOMP)Mbp}/Jam2^{tm1.1(KOMP)Mbp} C57BL/6N-Jam2^{tm1.1(KOMP)Mbp}/J	abnormal retina morphology	J:211773
	increased circulating potassium level	J:211773
	increased circulating sodium level	J:211773
	increased heart weight	J:211773
Jam2^tm1.2Rha/Jam2^tm1.2Rha B6.Cg-Jam2^tm1.2Rha	abnormal bone marrow cell morphology/development	J:178387
	abnormal hematopoietic stem cell morphology	J:178387
	abnormal hematopoietic stem cell physiology	J:178387
	decreased osteoblast cell number	J:178387
	increased bone marrow cell number	J:178387
	increased mortality induced by ionizing radiation	J:178387
	increased susceptibility to xenobiotic induced morbidity/mortality	J:178387
Jam2^tm1Okud/Jam2^tm1Okud involves: C57BL/6 * CBA	no abnormal phenotype detected	J:112136

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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