Alms1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Alms1
ALMS1, centrosome and basal body associated
MGI:1934606

55 phenotypes from 12 alleles in 12 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Alms1^bbb/Alms1^bbb C57BL/6JSfdAnu-Alms1^bbb/Anu	abnormal eye physiology	J:104190
	hyperglycemia	J:104190
	impaired hearing	J:104190
	increased circulating insulin level	J:104190
	obese	J:104190
	small gonad	J:104190
Alms1^foz/Alms1^foz involves: NOD	abnormal hepatocyte morphology	J:107058
	enlarged liver	J:107058
	hepatic steatosis	J:107058
	hyperglycemia	J:107058
	increased circulating insulin level	J:107058
	increased food intake	J:107058
	increased liver weight	J:107058
	insulin resistance	J:107058
	liver fibrosis	J:107058
Alms1^Gt(XH152)Byg/Alms1^Gt(XH152)Byg involves: 129P2/OlaHsd * C57BL/6J	abnormal eye electrophysiology	J:100403
	abnormal retina outer nuclear layer morphology	J:100403
	abnormal seminiferous tubule morphology	J:100403
	albuminuria	J:100403
	normal cellular phenotype	J:100403
	crystalluria	J:100403
	degranulated pancreatic beta cells	J:100403
	dilated proximal convoluted tubule	J:100403
	enlarged kidney	J:100403
	hyperglycemia	J:100403
	increased body weight	J:100403
	increased circulating cholesterol level	J:100403
	increased circulating insulin level	J:100403
	increased kidney weight	J:100403
	increased liver weight	J:100403
	increased or absent threshold for auditory brainstem response	J:100403
	increased white adipose tissue amount	J:100403
	macrovesicular hepatic steatosis	J:100403
	microvesicular hepatic steatosis	J:100403
	obese	J:100403
	pancreatic islet hyperplasia	J:100403
	small gonad	J:100403
	tubulointerstitial nephritis	J:100403
Alms1^L2131X/Alms1^L2131X involves: C57BL/6 * NOD	abnormal circulating cholesterol level	J:118221
	abnormal eye physiology	J:118221
	abnormal proximal convoluted tubule morphology	J:118221
	abnormal renal tubule epithelial cell primary cilium morphology	J:118221
	abnormal spermatogenesis	J:118221
	dilated renal tubule	J:118221
	hepatic steatosis	J:118221
	increased circulating HDL cholesterol level	J:118221
	increased circulating insulin level	J:118221
	increased circulating leptin level	J:118221
	increased circulating triglyceride level	J:118221
	increased fat cell size	J:118221
	increased kidney apoptosis	J:118221
	increased kidney cell proliferation	J:118221
	increased susceptibility to weight gain	J:118221
	increased total body fat amount	J:118221
	increased urine protein level	J:118221
	seminiferous tubule degeneration	J:118221
Alms1^m1Btlr/Alms1^m1Btlr C57BL/6J-Alms1^m1Btlr	increased body weight	J:218964
Alms1^m2Btlr/Alms1^m2Btlr C57BL/6J-Alms1^m2Btlr	impaired glucose tolerance	J:264648
Alms1^m3Btlr/Alms1^m3Btlr C57BL/6J-Alms1^m3Btlr	impaired glucose tolerance	J:264649
	increased body size	J:264649
	increased body weight	J:264649
	increased circulating insulin level	J:264649
	increased fasting circulating glucose level	J:264649
Alms1^m4Btlr/Alms1^m4Btlr C57BL/6J-Alms1^m4Btlr	increased body weight	J:267551
Alms1^m5Btlr/Alms1^m5Btlr C57BL/6J-Alms1^m5Btlr	increased body weight	J:267682
Alms1^m6Btlr/Alms1^m6Btlr C57BL/6J-Alms1^m6Btlr	increased body weight	J:274969
Alms1^{tm1b(EUCOMM)Hmgu}/Alms1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Alms1^{tm1b(EUCOMM)Hmgu}/H	abnormal locomotor behavior	J:211773
	increased circulating amylase level	J:211773
Alms1^tvrm102/Alms1^Gt(XH152)Byg involves: 129P2/OlaHsd * C57BL/6J	obese	J:243745
	retina photoreceptor degeneration	J:243745
Alms1^tvrm102/Alms1^tvrm102 C57BL/6J-Alms1^tvrm102/Pjn	increased susceptibility to age-related retinal degeneration	J:243745
	obese	J:243745
	retina outer nuclear layer degeneration	J:243745
	retina photoreceptor degeneration	J:243745
	retina pigment epithelium atrophy	J:243745

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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