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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Nucks1
nuclear casein kinase and cyclin-dependent kinase substrate 1
MGI:1934811
35 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Nucks1tm1.2Vter/Nucks1tm1.2Vter
involves: 129S2/SvPas * C57BL/6 * C57BL/6NSlc * FVB/N * SJL 		decreased basal metabolism J:211777
decreased circulating adiponectin level J:211777
decreased energy expenditure J:211777
decreased locomotor activity J:211777
normal embryo phenotype J:211777
hepatic steatosis J:211777
normal homeostasis/metabolism phenotype J:211777
impaired glucose tolerance J:211777
increased body weight J:211777
increased circulating glucose level J:211777
increased circulating insulin level J:211777
increased circulating leptin level J:211777
increased food intake J:211777
increased pulmonary respiratory rate J:211777
increased renal fat pad weight J:211777
increased total body fat amount J:211777
insulin resistance J:211777
Nucks1tm1b(EUCOMM)Hmgu/Nucks1tm1b(EUCOMM)Hmgu
C57BL/6N-Nucks1tm1b(EUCOMM)Hmgu/Ieg 		abnormal eye morphology J:211773
abnormal jejunum morphology J:211773
abnormal kidney morphology J:211773
abnormal stomach morphology J:211773
abnormal vibrissa morphology J:211773
decreased circulating chloride level J:211773
decreased circulating cholesterol level J:211773
decreased circulating glucose level J:211773
decreased circulating HDL cholesterol level J:211773
decreased circulating triglyceride level J:211773
decreased grip strength J:211773
enlarged lymph nodes J:211773
increased circulating cholesterol level J:211773
increased circulating creatinine level J:211773
increased lean body mass J:211773
increased leukocyte cell number J:211773
persistence of hyaloid vascular system J:211773
preweaning lethality, incomplete penetrance J:211773
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory