Bbs2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Bbs2
Bardet-Biedl syndrome 2
MGI:2135267

44 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Bbs2^{em2(IMPC)Wtsi}/Bbs2⁺ C57BL/6N-Bbs2^{em2(IMPC)Wtsi}/Wtsi	decreased lean body mass	J:211773
	increased bone mineral content	J:211773
Bbs2^tm1.1Huss/Bbs2^tm1.1Huss involves: 129S6/SvEv * C57BL/6	abnormal olfactory epithelium cilium morphology	J:296033
	abnormal olfactory epithelium morphology	J:296033
	abnormal primary cilium morphology	J:296033
	anosmia	J:296033
	decreased birth body size	J:296033
	decreased retina cone cell number	J:296033
	decreased retina rod cell number	J:296033
	increased ceramide level	J:296033
	increased circulating alanine transaminase level	J:296033
	increased circulating leptin level	J:296033
	increased circulating triglyceride level	J:296033
	increased fat cell size	J:296033
	increased liver weight	J:296033
	increased total body fat amount	J:296033
	obese	J:296033
	polyphagia	J:296033
	normal renal/urinary system phenotype	J:296033
	retina outer nuclear layer degeneration	J:296033
	thin retina outer nuclear layer	J:296033
Bbs2^tm1Vcs/Bbs2^tm1Vcs either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)	abnormal abdominal fat pad morphology	J:94467
	abnormal eye electrophysiology	J:94467
	abnormal olfaction	J:94467
	abnormal placing response	J:94467
	absent sperm flagellum	J:94467
	decreased aggression	J:94467
	decreased birth body size	J:94467
	decreased body size	J:94467
	decreased salivation	J:94467
	decreased startle reflex	J:94467
	disorganized photoreceptor outer segment	J:94467
	hepatic steatosis	J:94467
	hyporesponsive to tactile stimuli	J:94467
	increased body mass index	J:94467
	increased body weight	J:94467
	increased susceptibility to age-related retinal degeneration	J:94467
	kidney cyst	J:94467
	normal limbs/digits/tail phenotype	J:94467
	male infertility	J:94467
	polyphagia	J:94467
Bbs2^tm1Vcs/Bbs2^tm1Vcs involves: 129S1/Sv * 129X1/SvJ	abnormal basal ganglion morphology	J:128532
	enlarged lateral ventricles	J:128532
	enlarged third ventricle	J:128532
	small hippocampus	J:128532
	thin cerebral cortex	J:128532

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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