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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Lmod2
leiomodin 2 (cardiac)
MGI:2135672
25 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Lmod2tm1(KOMP)Vlcg/Lmod2tm1(KOMP)Vlcg
involves: C57BL/6J * C57BL/6NTac 		abnormal fetal cardiomyocyte morphology J:227272
abnormal heart ventricle morphology J:227272
abnormal intercalated disk morphology J:227272
abnormal myocardial fiber morphology J:227272
abnormal sarcomere morphology J:227272
abnormal Z line morphology J:227272
decreased cardiac muscle contractility J:227272
decreased heart left ventricle wall thickness J:227272
decreased mitochondrial number J:227272
dilated cardiomyopathy J:227272
dilated heart J:227272
dilated heart left ventricle J:227272
increased heart weight J:227272
postnatal lethality, incomplete penetrance J:227272
premature death J:227272
thin ventricular wall J:227272
Lmod2Tn(pb-Act-RFP)1.1Zhu/Lmod2Tn(pb-Act-RFP)1.1Zhu
involves: FVB/N 		abnormal intercalated disk morphology J:233669
abnormal myocardial fiber morphology J:233669
abnormal sarcomere morphology J:233669
abnormal Z line morphology J:233669
absent M line J:233669
congestive heart failure J:233669
decreased body weight J:233669
decreased cardiac muscle contractility J:233669
decreased locomotor activity J:233669
dilated cardiomyopathy J:233669
dilated heart ventricle J:233669
increased heart weight J:233669
irregular heartbeat J:233669
premature death J:233669
prolonged QT interval J:233669
respiratory distress J:233669
thin ventricular wall J:233669
trunk curl J:233669
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory