Sarm1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sarm1
sterile alpha and HEAT/Armadillo motif containing 1
MGI:2136419

14 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Sarm1^tm1.1Diam/Sarm1^tm1.1Diam involves: 129X1/SvJ * C57BL/6	abnormal circulating tumor necrosis factor level	J:200140
	abnormal nervous system physiology	J:196200
	decreased microglial cell activation	J:200140
	decreased neuron apoptosis	J:196200
	normal hematopoietic system phenotype	J:200140
	normal immune system phenotype	J:196200, J:200140
	increased neuron apoptosis	J:200140
	increased susceptibility to Flaviviridae infection	J:200140
	increased susceptibility to Flaviviridae infection induced morbidity/mortality	J:200140
Sarm1^tm1Aidi/Sarm1^tm1Aidi involves: 129X1/SvJ * C57BL/6J	decreased apoptosis	J:126083
Sarm1^tm1Aidi/Sarm1^tm1Aidi involves: 129X1/SvJ * C57BL/6J	normal immune system phenotype	J:126083
Tg(UBB-EmGFP/RNAi:Sarm1)#Yph/0 involves: C57BL/6J	abnormal dendrite morphology	J:172355
	decreased brain size	J:172355
	decreased brain weight	J:172355
	small hippocampus	J:172355

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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