Setd4 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Setd4
SET domain containing 4
MGI:2136890

9 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Setd4^{tm1a(KOMP)Wtsi}/Setd4^{tm1a(KOMP)Wtsi} C57BL/6N-Setd4^{tm1a(KOMP)Wtsi}/Wtsi	decreased fasting circulating glucose level	J:211773
	increased circulating aspartate transaminase level	J:211773
Setd4^{tm1b(KOMP)Wtsi}/Setd4^{tm1b(KOMP)Wtsi} involves: C57BL/6N	decreased macrophage cytokine production	J:304151
Setd4^{tm1c(KOMP)Wtsi}/Setd4^{tm1c(KOMP)Wtsi} Gt(ROSA)26Sor^{tm1(cre/ERT2)Tyj}/Gt(ROSA)26Sor⁺ involves: 129S4/SvJae * C57BL/6 * C57BL/6N	abnormal tumor pathology	J:297725
	decreased apoptosis	J:297725
	decreased mortality induced by ionizing radiation	J:297725
	decreased tumor growth/size	J:297725
	increased metastatic potential	J:297725
	increased tumor latency	J:297725

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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