Kdm5a Phenotype Annotations

About Help FAQ

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kdm5a
lysine demethylase 5A
MGI:2136980

10 phenotypes from 2 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Kdm5a^tm1.1Kael/Kdm5a^tm1.1Kael B6.129S6-Rbp2^tm1.1Kael	neonatal lethality, complete penetrance	J:137333
Kdm5a^tm1.1Kael/Kdm5a^tm1.1Kael involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL	abnormal behavior	J:137185, J:137333
	abnormal cell cycle	J:137185
	abnormal definitive hematopoiesis	J:137185
	abnormal hematopoietic stem cell morphology	J:137185
	abnormal involuntary movement	J:137333
	decreased body size	J:137333
	increased neutrophil cell number	J:137185
Kdm5a^tm1.1Kael/Kdm5a^tm1.1Kael involves: 129S6/SvEvTac * FVB/N	early cellular replicative senescence	J:175625
Kdm5a^tm1Kael/Kdm5a^tm1Kael involves: 129S6/SvEvTac * C57BL/6 * CBA	early cellular replicative senescence	J:175625
Kdm5a^tm1Kael/Kdm5a^tm1Kael involves: 129S6/SvEvTac * C57BL/6 * FVB/N	no abnormal phenotype detected	J:137185
Kdm5a^tm1Kael/Kdm5a^tm1Kael Tg(CAG-cre/Esr1)5Amc/0 involves: 129S6/SvEvTac C57BL/6 * CBA	early cellular replicative senescence	J:175625

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24