P2rx5 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

P2rx5
purinergic receptor P2X, ligand-gated ion channel, 5
MGI:2137026

7 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
P2rx5^{tm1b(EUCOMM)Hmgu}/P2rx5⁺ C57BL/6N-P2rx5^{tm1b(EUCOMM)Hmgu}/Ieg	abnormal gait	J:211773
	decreased exploration in new environment	J:211773
P2rx5^{tm1b(EUCOMM)Hmgu}/P2rx5^{tm1b(EUCOMM)Hmgu} C57BL/6N-P2rx5^{tm1b(EUCOMM)Hmgu}/Ieg	preweaning lethality, incomplete penetrance	J:211773
P2rx5^tm1Lex/P2rx5^tm1Lex involves: 129S5/SvEvBrd * C57BL/6J	decreased CD8-positive, alpha-beta T cell number	J:82809
	impaired cued conditioning behavior	J:82809
	increased exploration in new environment	J:82809
	increased NK cell number	J:82809

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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