Trim33 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Trim33
tripartite motif-containing 33
MGI:2137357

27 phenotypes from 6 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(CAG-cre)13Miya/0 Trim33^tm1.1Los/Trim33^tm1.2Los involves: 129 * 129S2/SvPas * C57BL/6 * SJL	abnormal anterior visceral endoderm morphology	J:163858
	abnormal embryo development	J:163858
Trim33^em1(IMPC)Tcp/Trim33⁺ C57BL/6N-Trim33^em1(IMPC)Tcp/Tcp	cornea opacity	J:211773
	enlarged lymph nodes	J:211773
Trim33^em1(IMPC)Tcp/Trim33^em1(IMPC)Tcp C57BL/6N-Trim33^em1(IMPC)Tcp/Tcp	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Trim33^tm1.1Los/Trim33^tm1.2Los Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ involves: 129S2/SvPas * C57BL/6 * CBA * SJL	abnormal brain development	J:163858
	abnormal endoderm development	J:163858
	abnormal mesendoderm development	J:163858
	abnormal primitive node morphology	J:163858
	abnormal primitive streak elongation	J:163858
	decreased embryo size	J:163858
	normal embryo phenotype	J:163858
	embryonic lethality, incomplete penetrance	J:163858
	incomplete rostral neuropore closure	J:163858
Trim33^tm1.1Vk/Trim33^tm1.1Vk involves: 129S2/SvPas * FVB/N	embryonic growth retardation	J:137219
Trim33^tm1.1Vk/Trim33^tm1.1Vk involves: 129S2/SvPas * FVB/N	embryonic lethality between somite formation and embryo turning, complete penetrance	J:137219
Trim33^tm1.2Los/Trim33^tm1.2Los involves: 129S2/SvPas * C57BL/6 * SJL	abnormal anterior visceral endoderm morphology	J:163858
	abnormal developmental patterning	J:163858
	abnormal embryonic-extraembryonic boundary morphology	J:163858
	abnormal mesoderm development	J:163858
	abnormal proamniotic cavity morphology	J:163858
	absent extraembryonic ectoderm	J:163858
	decreased embryo size	J:163858
	embryonic lethality between implantation and somite formation, complete penetrance	J:163858
	failure of primitive streak formation	J:163858
Trim33^tm1Los/Trim33^tm1Los Tg(Cd4-cre)1Cwi/0 involves: 129S2/SvPas * C57BL/6 * DBA/2	normal immune system phenotype	J:149449
Trim33^tm1Los/Trim33^tm1Los Tg(Pdx1-cre)89.1Dam/0 involves: 129S2/SvPas * C57BL/6 * DBA/2	normal endocrine/exocrine gland phenotype	J:151781
Trim33^tm1Vk/Trim33^tm1Vk involves: 129S2/SvPas	no abnormal phenotype detected	J:137219

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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